Review the
side-effects of Nintedanib as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your
doctor or pharmacist.
Gastrointestinal: Diarrhea, vomiting, nausea, stomach pain, loss of appetite
Nervous system: Headache, peripheral neuropathy, sudden numbness
Cardiovascular: Increased blood pressure, blood clots
Respiratory: Tightness of the chest,
cough
Others: Abnormal levels of liver enzymes, Rashes, mucositis, itching, weight gain
Other Precautions : Women who become pregnant during the treatment with nintedanib should inform the doctor immediately.
Extreme caution is required while giving nintedanib to patients with severe kidney damage or patients who undergo dialysis.
Patients with a smoking history are advised to stop smoking before initiating the nintedanib treatment as smoking can decrease the effectiveness of nintedanib resulting in treatment failure.
There is no specific antidote for nintedanib overdose. Therefore patients must be treated with general supportive measures appropriately.
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