Side effect(s) of Neratinib

Last Updated on Mar 21, 2023

Review the side-effects of Neratinib as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Common: Diarrhea, nausea, stomach pain, fatigue, vomiting, muscle pain, weight loss

  Gastrointestinal: Dry mouth, upset stomach, stomatitis, reduced appetite

  Cardiovascular: Low blood pressure

  Respiratory: Bleeding from the nose

  Skin: Rashes, dry skin, skin fissures, nail disorders, skin infection

  Others: Increased level of liver enzymes, urinary tract infection, dehydration, kidney failure

Other Precautions :

• Do not stop taking or change the dose of neratinib without physician’s advice.
• Follow a special diet as advised to avoid or to control diarrhea.
• Drink plenty of fluids while on neratinib treatment.
• Seek or call an emergency center for help when serious side effects occur or medical attention if required.

Drug Name : Neratinib

Neratinib generic Neratinib is prescribed as an adjuvant therapy to treat adult patients with an early stage HER2 - positive breast cancer who have been already treated with trastuzumab therapy at least for a year. Neratinib is a kinase inhibitor that acts by binding to certain proteins called Human Epidermal Growth Factor Receptor 2 (HER2), Epidermal Growth Factor Receptor (EGFR), and HER4 which is responsible for the growth of cancer cells.

Last Updated on Mar 21, 2023