Naftopidil generic Naftopidil is a selective α1-adrenergic receptor antagonist or alpha blocker. Naftopidil is prescribed in Japan for the treatment of benign prostatic hyperplasia (BPH) and benign prostatic obstruction, associated with lower urinary tract symptoms (LUTS), hypertension , cardiac valve disease, and distal ureteral stones. Further large-scale, randomized, placebo-controlled studies need to be done to see if the naftopidil efficacy and safety data that is applicable to Japanese can be extended to white, black and Hispanic men having LUTS/BPH in western countries.
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