Review the side-effects of Ivosidenib as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Gastrointestinal: Stomach pain, diarrhea, nausea, vomiting, constipation, mucositis, loss of appetite
Nervous system: Fever, headache, fatigue, numbness and pricking sensation, changes in taste, vision, touch or hearing
Cardiovascular: Irregular heart rhythm, reduction in blood pressure, fainting while standing suddenly, fluid accumulation, swelling of legs
Respiratory: Chest pain, cough, breathing difficulty, fluid buildup around lung cavity
Musculoskeletal: Muscle pain, muscle weakness, pain in the joints, neck pain, muscle stiffness, pain in the legs or hands
Others: Rashes, abnormal lab values of hemoglobin, liver enzymes, sodium, magnesium, potassium, uric acid, phosphate, and bilirubin
• Ivosidenib can affect fertility in men and women of reproductive potential; therefore patients must be advised about sperm or egg banking preservation for later use when they decide to have a child.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Gastrointestinal: Stomach pain, diarrhea, nausea, vomiting, constipation, mucositis, loss of appetite
Nervous system: Fever, headache, fatigue, numbness and pricking sensation, changes in taste, vision, touch or hearing
Cardiovascular: Irregular heart rhythm, reduction in blood pressure, fainting while standing suddenly, fluid accumulation, swelling of legs
Respiratory: Chest pain, cough, breathing difficulty, fluid buildup around lung cavity
Musculoskeletal: Muscle pain, muscle weakness, pain in the joints, neck pain, muscle stiffness, pain in the legs or hands
Others: Rashes, abnormal lab values of hemoglobin, liver enzymes, sodium, magnesium, potassium, uric acid, phosphate, and bilirubin
Other Precautions :
• A blood test should be performed before and during the treatment with ivosidenib to detect any blood disorders. In such cases, the dose can either be reduced or the treatment can be stopped temporarily or permanently.• Ivosidenib can affect fertility in men and women of reproductive potential; therefore patients must be advised about sperm or egg banking preservation for later use when they decide to have a child.
