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Side effect(s) of Isotretinoin


Review the side-effects of Isotretinoin as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

   Body as a Whole
- Allergic reactions.

   Heart
- Palpitations, fast heart rate and stroke.

   Metabolic
- Increased blood cholesterol level.

   Gastrointestinal
- Inflammatory bowel disease, bleeding, inflammation of the gums, peptic ulcer and nausea.

   Musculoskeletal
- Bone weakness, calcification of tendons and ligaments, premature epiphyseal closure, decrease in bone mineral density including muscle/joint pain.

   Central Nervous System
- Dizziness, drowsiness, headache, insomnia, lethargy, uneasiness, nervousness, tingling, seizures, stroke, fainting, weakness, suicidal thoughts, suicide attempts, depression, psychosis, aggression and violent behaviors.

   Genitourinary
- Abnormal menses.

   Respiratory
- Asthma.

Other Precautions :

It may cause the bones to weaken or thicken abnormally and may increase the risk of certain bone injuries in people who perform some types of physical activity. Consult with your doctor before performing such activities.

Drug Name : Isotretinoin

Isotretinoin(Amnesteem) generic is a retinoid, prescribed for acne and other skin disorders. It reduces skin oil production, changing the characteristics of the skin oil, and preventing abnormal hardening of the skin.


Trade Names for Isotretinoin

India :


International :


Amnesteem, Claravis, Sotret
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