Read the side effects of Estradiol as described in the medical literature. In case of any doubt consult your doctor or pharmacist.
Central Nervous System
Headache, dizziness, sleeplessness, depression, anxiety, nervousness, migraine.
Abdominal distension, abdominal pain, flatulence, nausea, constipation, upset stomach , diarrhea, bleeding, toothache, tooth disorder.
Rash, itching, inflammation of the skin, skin scar.
Temporary loss of consciousness and posture, vein inflammation.
Abnormal bleeding during menstrual cycles, breast pain, breast tenderness, vaginal bleeding, vaginal discomfort, blood in urine, urinary incontinence.
Other Precautions :
*Monitor blood sugar level regularly, in case if you have diabetes.