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Side effect(s) of Cobimetinib


Review the side-effects of Cobimetinib as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Gastrointestinal
: Diarrhea, nausea , vomiting, stomatitis (inflammation in the mucosa of mouth)

  Eye
: Vision impairment, retinal diseases

  Cardiovascular
: Hypertension, blood loss (hemorrhage)

  Skin
: Photosensitivity (allergy to sunlight), acne (pimples)

  Others
: Fever (pyrexia) or chills

  Lab abnormalities
: liver function tests (AST, ALT), creatine phosphokinase, levels of phosphorous, sodium, potassium, calcium in the blood.
Hemoglobin and lymphocytes through blood test should be monitored regularly.

Other Precautions :

Cobimetinib should not be prescribed to pregnant and breastfeeding women.
Cobimetinib should not be used in children.

Drug Name : Cobimetinib

Cobimetinib is an anti-cancer drug used along with vemurafenib for the treatment of patients with melanoma (cancer of the skin) that cannot be surgically removed or melanoma that has spread to other parts of the body.


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