Side effect(s) of Cephaloridine

Review the side-effects of Cephaloridine as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
• Cefaloridine has marked dose-related nephrotoxicity.
• The drug accumulates in the proximal renal tubular cell, probably by active anionic transport.
Probenecid, which blocks such transport, is given to patients to eliminate the nephrotoxicity of cephaloridine when it occurs.

• Other side effects common to first-generation cephalosporin class of antibiotics are
Diarrhea, nausea, rash, pain and inflammation at the injection site

Pseudomembranous colitis (inflammation of the colon)

  Hematological disorders:
Esinophilia, low levels of prothrombin, abnormalities of blood coagulation

  Nephrological disorder:
Renal damage at large doses

Vomiting, headache, dizziness, fungal infections of the mouth and vagina, fever

• Certain complications that maybe caused by the use of cephaloridine include seizures, coma, chronic renal failure, acute renal failure and death.

Other Precautions :

• The entire course of this antibiotic should be completed even if the patients feel better; this will make sure the infection is cured.
• There have been instances of renal tubular necrosis with uremia and death after large doses in some patients with progressive renal disease, and toxic effects on the central nervous system after intrathecal administration.

Drug Name : Cephaloridine

Cephaloridine generic Cephaloridine, administered parenterally was used for bacterial infections, like lower respiratory tract, skin and urinary tract infections (before 1970s). It is no longer available for therapeutic use. Cephaloridine acts like other cephalosporin and penicillin antibiotics by interfering with the final step of bacterial cell wall synthesis. As a result the cell wall weakens and cell lysis occurs. Cephaloridine is more commonly used in veterinary practice to treat mild to severe bacterial infections caused by penicillin resistant and penicillin sensitive bacterial species.

Trade Names for Cephaloridine

India :