Review the side-effects of Brexanolone as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist. Sleepiness
Dry mouth
Loss of consciousness
Flushing of face or skin
2.During infusion of the drug patients should have continuous pulse oximetry monitoring. Immediately stop the infusion if pulse oximeter shows low oxygen saturation.
3.During interactions, patients can bring their babies however a caregiver or relative must be present to take care of the baby when the patient is receiving an infusion of brexanolone.
4.Brexanolone is available only through a restricted program under REMS called ZULRESSO REMS as the sudden loss of consciousness and excessive sedation can cause serious harm.
5.Brexanolone can increase the risk of suicidal thoughts or actions in some people 24 years of age and younger. Patients should inform the healthcare provider of any changes especially sudden changes in mood, behavior, thoughts, or feelings, or if they develop suicidal thoughts or actions.
6.Inform the healthcare provider about all the previous or present medical conditions, alcohol consumption, if there are any kidney problems, are pregnant, are breastfeeding, or plan to breastfeed.
7.Inform the healthcare provider if the medications like antidepressants, opioids, and other CNS depressants like benzodiazepines like alprazolam, diazepam or clonazepam are being taken.
8.After receiving brexanolone infusion, do not drive until the feeling of sleepiness is completely gone.
9.Do not consume alcohol while receiving Brexanolone infusion.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist. Sleepiness
Dry mouth
Loss of consciousness
Flushing of face or skin
Other Precautions :
1.During Brexanolone infusion, patients are at an increased risk for the excessive and sudden loss of consciousness and the patients should be monitored for the same.2.During infusion of the drug patients should have continuous pulse oximetry monitoring. Immediately stop the infusion if pulse oximeter shows low oxygen saturation.
3.During interactions, patients can bring their babies however a caregiver or relative must be present to take care of the baby when the patient is receiving an infusion of brexanolone.
4.Brexanolone is available only through a restricted program under REMS called ZULRESSO REMS as the sudden loss of consciousness and excessive sedation can cause serious harm.
5.Brexanolone can increase the risk of suicidal thoughts or actions in some people 24 years of age and younger. Patients should inform the healthcare provider of any changes especially sudden changes in mood, behavior, thoughts, or feelings, or if they develop suicidal thoughts or actions.
6.Inform the healthcare provider about all the previous or present medical conditions, alcohol consumption, if there are any kidney problems, are pregnant, are breastfeeding, or plan to breastfeed.
7.Inform the healthcare provider if the medications like antidepressants, opioids, and other CNS depressants like benzodiazepines like alprazolam, diazepam or clonazepam are being taken.
8.After receiving brexanolone infusion, do not drive until the feeling of sleepiness is completely gone.
9.Do not consume alcohol while receiving Brexanolone infusion.
