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Side effect(s) of Brexanolone

Read the side effects of Brexanolone as described in the medical literature. In case of any doubt consult your doctor or pharmacist.

Sleepiness

Dry mouth

Loss of consciousness

Flushing of face or skin

Other Precautions : 1.During Brexanolone infusion, patients are at an increased risk for the excessive and sudden loss of consciousness and the patients should be monitored for the same.

2.During infusion of the drug patients should have continuous pulse oximetry monitoring. Immediately stop the infusion if pulse oximeter shows low oxygen saturation.

3.During interactions, patients can bring their babies however a caregiver or relative must be present to take care of the baby when the patient is receiving an infusion of brexanolone.

4.Brexanolone is available only through a restricted program under REMS called ZULRESSO REMS as the sudden loss of consciousness and excessive sedation can cause serious harm.

5.Brexanolone can increase the risk of suicidal thoughts or actions in some people 24 years of age and younger. Patients should inform the healthcare provider of any changes especially sudden changes in mood, behavior, thoughts, or feelings, or if they develop suicidal thoughts or actions.

6.Inform the healthcare provider about all the previous or present medical conditions, alcohol consumption, if there are any kidney problems, are pregnant, are breastfeeding, or plan to breastfeed.

7.Inform the healthcare provider if the medications like antidepressants, opioids, and other CNS depressants like benzodiazepines like alprazolam, diazepam or clonazepam are being taken.

8.After receiving brexanolone infusion, do not drive until the feeling of sleepiness is completely gone.

9.Do not consume alcohol while receiving Brexanolone infusion.

Drug Name : Brexanolone

Brexanolone is indicated for the treatment of postpartum depression (PPD) among women.
More Info about Brexanolone

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