Review the side-effects of Blinatumomab as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Nervous system: Confusion, headache, dizziness, tremor, inability to sleep, altered state of consciousness, seizures, speech disorder, mood disorders such as depression and suicidal thoughts
Blood: Fluctuations in blood pressure, abnormal heart rhythm, blood disorders
Respiratory: Difficulty in breathing, cough, wheezing, chest tightness, respiratory failure
Lab abnormalities: Abnormal levels of bilirubin, alkaline phosphatase, liver enzymes, neutrophils, gammaglobulin, immunoglobulin
Others: Infections, fever, muscle pain, bone pain, rashes, infusion-related reactions, decreased weight, pain in the legs and hands
• The infusion mixture stored in cold storage or refrigerator should be allowed to come to room temperature before administering to the patient.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Nervous system: Confusion, headache, dizziness, tremor, inability to sleep, altered state of consciousness, seizures, speech disorder, mood disorders such as depression and suicidal thoughts
Blood: Fluctuations in blood pressure, abnormal heart rhythm, blood disorders
Respiratory: Difficulty in breathing, cough, wheezing, chest tightness, respiratory failure
Lab abnormalities: Abnormal levels of bilirubin, alkaline phosphatase, liver enzymes, neutrophils, gammaglobulin, immunoglobulin
Others: Infections, fever, muscle pain, bone pain, rashes, infusion-related reactions, decreased weight, pain in the legs and hands
Other Precautions :
• During the treatment with blinatumomab, efforts should be taken to minimize administration errors such as overdose or low dose and to avoid contamination during the preparation.• The infusion mixture stored in cold storage or refrigerator should be allowed to come to room temperature before administering to the patient.