Side effect(s) of Benznidazole

Read the side effects of Benznidazole as described in the medical literature. In case of any doubt consult your doctor or pharmacist.
Common: Weight loss, rash, pain in the abdomen, headache



Gastrointestinal: Loss of appetite, diarrhea, vomiting, nausea, pain in the abdomen, dry mouth

Central nervous system: Peripheral neuropathy, paresthesia, dizziness, headache, confusion, inability to concentrate, tremor. The treatment should be stopped if neurological symptoms appear.

Blood: Reduced blood counts of red blood cells, white blood cells and platelets, eosinophilia

Skin: Rashes, eczema, allergic or exfoliative dermatitis, itching, toxic epidermal necrolysis, erythema multiforme, peeling of skin. The treatment should be discontinued if the skin reactions are associated with lymph node enlargement, fever and/or purpura (small purple spots due to small bleeds under the skin).



Others: Edema, fever, muscle pain, hepatitis, fatigue, asthenia, allergic reaction, increased levels of alkaline phosphatase and bilirubin, joint pain

Other Precautions :  Adverse reactions should be reported to the emergency center as early as possible.
Tablets of benznidazole should be taken at least after 3 days of stopping alcohol consumption to avoid disulfiram-like reactions such as nausea, headache, abdominal cramps, and flushing.
Benznidazole 100 mg tablets are scored so that they are easy to break into either half or quarter as advised by the physician.
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