• Melitracen is available in an oral form as melitracen hydrochloride tablet (melitracen hydrochloride 28.1 mg is equivalent to about 25 mg of melitracen) and should be taken by mouth with a glass of water.
Adults: 25 mg tablet up to two or three times daily. The dose can be gradually increased to a total of 225 mg daily if necessary.
Elderly patients: Reduced doses of 25 or 30 mg daily initially
The recommended dose of melitracen and flupentixol combination drug is
Adults: Dose of 10 mg melitracen and 500 mg flupentixol orally in the morning and at midday. Morning dose can be doubled for severe cases.
Elderly patients:Adult dose is appropriate but only once in the morning. Only in severe cases, the dose has to be given in the afternoon too.
• When withdrawing the drug, do it gradually to reduce the risk of withdrawal symptoms.
• Hypersensitivity to the drug
• Myocardial infarction
• Narrow-angle glaucoma
• Bipolar disorder
• Epilepsy
• Who received monoamine oxidase inhibitors (MAOI) within two weeks
For those using the combination drug, it is contraindicated in patients:
• In the immediate recovery phase after myocardial infarction
• With defects in bundle-branch conduction
• With untreated narrow-angle glaucoma
• With acute alcohol, barbiturate and opiate intoxications
• Who received monoamine oxidase inhibitors (MAOI) within two weeks
The combination is not recommended for excitable or overactive patients since its activating effect may excite them more.
Dosage & When it is to be taken
The recommended dose of melitracen hydrochloride isAdults: 25 mg tablet up to two or three times daily. The dose can be gradually increased to a total of 225 mg daily if necessary.
Elderly patients: Reduced doses of 25 or 30 mg daily initially
The recommended dose of melitracen and flupentixol combination drug is
Adults: Dose of 10 mg melitracen and 500 mg flupentixol orally in the morning and at midday. Morning dose can be doubled for severe cases.
Elderly patients:Adult dose is appropriate but only once in the morning. Only in severe cases, the dose has to be given in the afternoon too.
• When withdrawing the drug, do it gradually to reduce the risk of withdrawal symptoms.
When it is not to be taken (Contraindications)
Melitracen is contraindicated in patients with• Hypersensitivity to the drug
• Myocardial infarction
• Narrow-angle glaucoma
• Bipolar disorder
• Epilepsy
• Who received monoamine oxidase inhibitors (MAOI) within two weeks
For those using the combination drug, it is contraindicated in patients:
• In the immediate recovery phase after myocardial infarction
• With defects in bundle-branch conduction
• With untreated narrow-angle glaucoma
• With acute alcohol, barbiturate and opiate intoxications
• Who received monoamine oxidase inhibitors (MAOI) within two weeks
The combination is not recommended for excitable or overactive patients since its activating effect may excite them more.