• Disodium edetate is given as an intravenous infusion only after dilution in 500 ml of 5% dextrose injection or 0.5% (0.9% for children) sodium chloride injection.
• It has to be administered only by a health care professional in a hospital or clinic setting. Final concentration for children should not be more than 3%.
Adults: Daily dose of 50 mg/kg per body weight up to a maximum dose of 3 kg in 24 hours
Children: Daily dose is 40 mg/kg per body weight up to a maximum dose of 70 mg/kg in 24 hours
• Allergic to the drug
• Who have problems in the passage of urine (anuria)
• For the treatment of generalized atherosclerosis (formation of plaque in blood vessels) that occurs due to old age
NOTE: Disodium edetate is strongly contraindicated to be used instead of the other EDTA agent, calcium disodium EDTA or calcium disodium versenate used to treat serious cases of lead poisoning, or to be used in non FDA approved "chelation therapies" that falsely claim to improve the cardiovascular system. Wrong uses of the drug in both the above cases have lead to fatalities in the past.
• It has to be administered only by a health care professional in a hospital or clinic setting. Final concentration for children should not be more than 3%.
Dosage & When it is to be taken
Dosage of disodium edetate injectionAdults: Daily dose of 50 mg/kg per body weight up to a maximum dose of 3 kg in 24 hours
Children: Daily dose is 40 mg/kg per body weight up to a maximum dose of 70 mg/kg in 24 hours
When it is not to be taken (Contraindications)
Disodium edetate is contraindicated in patients• Allergic to the drug
• Who have problems in the passage of urine (anuria)
• For the treatment of generalized atherosclerosis (formation of plaque in blood vessels) that occurs due to old age
NOTE: Disodium edetate is strongly contraindicated to be used instead of the other EDTA agent, calcium disodium EDTA or calcium disodium versenate used to treat serious cases of lead poisoning, or to be used in non FDA approved "chelation therapies" that falsely claim to improve the cardiovascular system. Wrong uses of the drug in both the above cases have lead to fatalities in the past.
