How to Take Atropine and diphenoxylate and Dose of Atropine and diphenoxylate

Written & Compiled by Madhumathi Palaniappan | Medically Reviewed by The Medindia Medical Review Team

Find out how to take Atropine and diphenoxylate (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Atropine and diphenoxylate

How it should be taken

It comes as a tablet to take by mouth, with or without food.

Dosage & When it is to be taken

In adults, the usual dose is 5 mg (2 tablets) three to four times per day initially. The dose for children is based on weight.

When it is not to be taken (Contraindications)

Contraindicated in patients with obstructive jaundice, pseudomembranous enterocolitis and hypersensitivity.

Why it is prescribed (Indications)

This medication is an antidiarrheal and anticholinergic combination, prescribed for diarrhea. Atropine works by reducing spasms where as Diphenoxylate decreases bowel movement.

Warnings and Precautions

Caution should be exercised in patients with history of lung disease, ulcerative colitis, or liver disease, alcohol abuse, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
Avoid hot weather; otherwise it may cause heatstroke.
It may cause fluid or electrolyte disturbances; if it so consult with your doctor.