How it should be taken
It comes as a capsule to take by mouth, with or without food.
Dosage & When it is to be taken
PO- The recommended dose is 125 mg, 1 hour prior to chemotherapy treatment (Day 1) and 80 mg orally once daily in the morning on Days 2 and 3.
The recommended oral dosage for post operative nausea is 40 mg within 3 hours prior to induction of anesthesia.
When it is not to be taken (Contraindications)
Contraindicated in patients who are taking astemizole, cisapride, pimozide, or terfenadine and hypersensitivity.
Why it is prescribed (Indications)
This medication is an antiemetic, prescribed for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) for prevention of postoperative nausea and vomiting and it is used with other medications to prevent nausea and vomiting that may occur within 24 hours after receiving cancer chemotherapy treatment.
Aprepitant works by blocking one of the body's natural substances (substance P/neurokinin 1) that causes vomiting
Warnings and Precautions
Caution should be exercised in patients with history of nausea or vomiting, liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Do not take aprepitant if you are on following medications, astemizole, cisapride, pimozide, or terfenadine.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
Store it at room temperature (20-25°C).