• Apalutamide tablets are available in tablet form and should be taken by mouth with food to avoid an upset stomach.
• Do not break or chew the tablets.
• Swallow the tablets as a whole with sufficient quantity of water.
• Patients taking apalutamide tablets should have had a bilateral orchiectomy or should receive an analog of gonadotropin-releasing hormone concurrently.
• Treatment should be withdrawn, if toxicity levels of grade 3 or more occur.
• The drug can be given as a regular or a reduced dose depending on the level of toxicity or to decrease the symptoms to grade 1 or even less.
• Patients allergic to the drug
• Female patients
• Men taking fertility treatments
• Patients having a history of seizures
• Patients with decreased bone density
• Children below 18 years of age
• Do not break or chew the tablets.
• Swallow the tablets as a whole with sufficient quantity of water.
Dosage & When it is to be taken
• The recommended dose of apalutamide is 240 mg (four tablets of 60 mg) and should be taken once a day.• Patients taking apalutamide tablets should have had a bilateral orchiectomy or should receive an analog of gonadotropin-releasing hormone concurrently.
• Treatment should be withdrawn, if toxicity levels of grade 3 or more occur.
• The drug can be given as a regular or a reduced dose depending on the level of toxicity or to decrease the symptoms to grade 1 or even less.
When it is not to be taken (Contraindications)
Apalutamide should not be used in-• Patients allergic to the drug
• Female patients
• Men taking fertility treatments
• Patients having a history of seizures
• Patients with decreased bone density
• Children below 18 years of age
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