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Tolbutamide : Interaction with Foods, Herbs & Alcohol


Are you taking Tolbutamide? Are you aware of the dangers of combining Tolbutamide with certain foods, herbs, or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.

Tolbutamide Interactions with Food and Herbs

Gingko biloba: Using Gingko biloba with Tolbutamide may result in decreased Tolbutamide plasma concentration.
Dong quai(Angelica sinensis or commonly known as female ginseng): Avoid using dong quai along with Tolbutamide as it may result in increased risk of hypoglycemia
Psyllium: Avoid using psyllium along with Tolbutamide, as it may result in increased risk of hypoglycemia.
Licorice: Use of licorice with antidiabetic drugs may decrease the effectiveness of the drug.
Glucomannan: Glucomannan when taken along with Tolbutamide can increase the risk of hypoglycemia.
Guar gum: Guar gum may decrease the effectiveness of Tolbutamide.
Bitter gourd: Taking Tolbutamide along with bitter gourd may result in increased risk of hypoglycemia
Fenugreek: Avoid intake of fenugreek along with antidiabetic agents as it may result in increased risk of hypoglycemia(1 Trusted Source
Tolbutamide: Micromedex Drug Information

Go to source
).

Tolbutamide Interactions with Alcohol

Avoid alcohol while taking Tolbutamide as it may increase the risk of prolonged hypoglycemia and disulfiram like reaction(1 Trusted Source
Tolbutamide: Micromedex Drug Information

Go to source
).

When and How to Take Tolbutamide

  • Tolbutamide is available in the form of a tablet to be taken once a day usually in the morning.
  • Follow the instructions as directed in the prescription label.
  • Do not exceed or miss the dose(2 Trusted Source
    Tolbutamide: Medlineplus Drug Information

    Go to source
    ).

References

1. Tolbutamide: Micromedex Drug Information
https://www.micromedexsolutions.com/micromedex2/librarian/PFDefaultActionId/evidencexpert.DoIntegratedSearch?navitem=topHome&isToolPage=true#
2. Tolbutamide: Medlineplus Drug Information
https://medlineplus.gov/druginfo/meds/a682481.html

Drug Name : Tolbutamide

Tolbutamide is an antidiabetic agent, prescribed for type 2 diabetes.
We recommend consulting your doctor to verify the information presented on this page or if you need any further clarifications.


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