Are you taking Theophylline ? Are you aware of the dangers of combining Theophylline with certain foods, herbs or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
Elgadir, M. A. (2019). Food-drug interaction and their clinical implications: Selected investigations.International Journal of Pharmacy and Pharmaceutical Sciences, 11(3), 1-5.doi:10.22159/ijpps.2019v11i3.25930
Go to source).
Tobacco: Using tobacco products like cigarettes along with theophylline may induce CYP1A2 metabolism.It may increase the serum concentration and cause toxicity (2✔ ✔Trusted Source
Zevin S, Benowitz NL. Drug interactions with tobacco smoking. Clin Pharmacokinet. 1999 (36), 425-438.
Go to source).
FDA. US Food and Drug Administration. Avoid food and drug interactions.
Go to source).
FDA. US Food and Drug Administration. Avoid food and drug interactions.
Go to source).
References
1. Elgadir, M. A. (2019). Food-drug interaction and their clinical implications: Selected investigations. International Journal of Pharmacy and Pharmaceutical Sciences, 11(3), 1-5. doi:10.22159/ijpps.2019v11i3.25930
2. Zevin S, Benowitz NL. Drug interactions with tobacco smoking. Clin Pharmacokinet. 1999 (36): 425-438. Available From: https://www.aafp.org/dam/AAFP/documents/patient_care/tobacco/drug-interactions.pdf
3. FDA. US Food and Drug Administration. Avoid food and drug interactions. Retrieved on 9th June 2022 from: https://curehht.org/wp-content/uploads/2017/11/Food_and_Drug_Interactions_FDA.pdf.
4. National Library of Medicine: Theophylline MedlinePlus Drug Information. Retrieved on 9th June 2022 from: https://medlineplus.gov/druginfo/meds/a681006.html#
Theophylline Interactions with Food and Herbs
High-fat meals: When theophylline is taken with a high-fat meal, which reduces the absorption of the medication, it can lead to nausea, vomiting, headache, and irritability (1✔ ✔Trusted SourceElgadir, M. A. (2019). Food-drug interaction and their clinical implications: Selected investigations.International Journal of Pharmacy and Pharmaceutical Sciences, 11(3), 1-5.doi:10.22159/ijpps.2019v11i3.25930
Go to source).
Tobacco: Using tobacco products like cigarettes along with theophylline may induce CYP1A2 metabolism.It may increase the serum concentration and cause toxicity (2✔ ✔Trusted Source
Zevin S, Benowitz NL. Drug interactions with tobacco smoking. Clin Pharmacokinet. 1999 (36), 425-438.
Go to source).
Theophylline Interactions with Alcohol
Interaction of theophylline with alcohol can lead to undesirable side effects such as nausea, vomiting, headache, and irritability (3✔ ✔Trusted SourceFDA. US Food and Drug Administration. Avoid food and drug interactions.
Go to source).
Theophylline Interactions with Caffeine
Avoid taking theophylline with caffeine-containing products such as coffee and tea, as it may cause some side effects like excitability, nervousness, and rapid heartbeat (3✔ ✔Trusted SourceFDA. US Food and Drug Administration. Avoid food and drug interactions.
Go to source).
When and How to Take Theophylline
- Theophylline is available only on prescription.
- It comes as an extended-release tablet and as a capsule and solution.
- Swallow the tablets as a whole instead of crushing, chewing, or breaking them.
- Do not exceed or skip the dose. Even if you miss it, take the medication as soon as you remember.
- Do not double the dose at a time to compensate for the missed dose (4✔ ✔Trusted Source
National Library of Medicine: Theophylline MedlinePlus Drug Information.
Go to source).
References
1. Elgadir, M. A. (2019). Food-drug interaction and their clinical implications: Selected investigations. International Journal of Pharmacy and Pharmaceutical Sciences, 11(3), 1-5. doi:10.22159/ijpps.2019v11i3.25930
2. Zevin S, Benowitz NL. Drug interactions with tobacco smoking. Clin Pharmacokinet. 1999 (36): 425-438. Available From: https://www.aafp.org/dam/AAFP/documents/patient_care/tobacco/drug-interactions.pdf
3. FDA. US Food and Drug Administration. Avoid food and drug interactions. Retrieved on 9th June 2022 from: https://curehht.org/wp-content/uploads/2017/11/Food_and_Drug_Interactions_FDA.pdf.
4. National Library of Medicine: Theophylline MedlinePlus Drug Information. Retrieved on 9th June 2022 from: https://medlineplus.gov/druginfo/meds/a681006.html#
