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Sertraline : Interaction with Food, Herbs, Alcohol and Caffeine


Interaction of Sertraline with Food, Herbs, Alcohol and Caffeine - For your own safety It is important to understand and avoid the drug-food interaction and how to take the medication. Drug-food interaction can sometimes cause side effects and can even reduce the efficacy of the drug.
Sertraline is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class, prescribed for major depression, obsessive-compulsive disorder, panic attacks, and social anxiety disorder. It increases the amounts of serotonin, a natural substance in the brain that helps maintain mental balance.

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Sertraline Interactions with Food and Herbs

Grapefruit Juice: Grapefruit juice increases the level in sertraline in the blood stream by inhibiting its metabolism.
St.John's Wort: Inform your doctor before taking St. John's Wort while taking sertraline.
Green Tea: Another herbal product to be avoided with sertraline is green tea. The combination may increase the risk of bleeding.
Cannabis sativa:You should not use cannabis while you are on sertraline since the combination may cause symptoms like confusion, panic, nervousness and anxiety.
Tyramine-Rich Food Products:Interaction between sertraline and tyramine-rich foods like cheese, milk, beef, chicken liver, meat extract, avocados, bananas, canned figs, soy beans and excess chocolate can result in a sudden and dangerous increase in blood pressure.

Sertraline Interactions with Alcohol

Alcohol may cause symptoms of depression and anxiety in patients taking sertraline.
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Sertraline Interactions with Caffeine

Avoid cola drinks, chocolate and caffeine containing food items with sertraline since the combination can result in a condition called serotonin syndrome with symptoms of high fever, agitation, vomiting, nausea, rapid heartbeat, trembling, sweating and weird movements on the muscles.

How to Take the Medication -

Sertraline is available as a tablet and a concentrated liquid and can be taken with food or on an empty stomach. Before using the liquid, it should be diluted with water, lemon/lime soda, ginger ale (carbonated soft drink) or lemonade. You should take only the recommended dose. If you are sensitive to latex, be careful while handling the dropper to dispense the liquid concentrate.
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