Are you taking Lorlatinib? Are you aware of the dangers of combining Lorlatinib with certain foods and herbs? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
St.John's wort: Avoid the use of St. John's wort with Lorlatinib as this may lower the levels of the drug in your body and makes it less effective. It may also increase the risk of changes in your liver function (1✔ ✔Trusted Source
Lorlatinib:Drug Information
Go to source).
References
1.Lorlatinib:Drug Information
https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210868s000lbl.pdf
2.Lorlatinib: Medlineplus Drug Information
https://medlineplus.gov/druginfo/meds/a619005.html#:~:text=Lorlatinib%20is%20in%20a%20class,signals%20cancer%20cells%20to%20multiply.
Lorlatinib Interactions with Food and Herbs
Grapefruit juice: Do not consume grapefruit or grapefruit juice with Lorlatinib it increases the blood levels and effects of the medication and results in a greater risk of side effects.St.John's wort: Avoid the use of St. John's wort with Lorlatinib as this may lower the levels of the drug in your body and makes it less effective. It may also increase the risk of changes in your liver function (1✔ ✔Trusted Source
Lorlatinib:Drug Information
Go to source).
When and How to Take Lorlatinib
- Lorlatinib comes as a tablet to be taken by mouth.
- It is usually taken once daily with or without food.
- Take Lorlatinib around the same time each day.
- Swallow the tablet whole, do not split, chew or crush it.
- Do not change the dose or stop taking the drug without consulting the physician.
- Follow the instructions exactly as directed.
- Do not take the tablet if it is already broken or cracked (2✔ ✔Trusted Source
Lorlatinib: Medlineplus Drug Information
Go to source).
References
1.Lorlatinib:Drug Information
https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210868s000lbl.pdf
2.Lorlatinib: Medlineplus Drug Information
https://medlineplus.gov/druginfo/meds/a619005.html#:~:text=Lorlatinib%20is%20in%20a%20class,signals%20cancer%20cells%20to%20multiply.
