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Buspirone : Interaction with Foods, Herbs & Alcohol


Are you taking Buspirone? Are you aware of the dangers of combining Buspirone with certain foods, herbs, or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.

Buspirone Interactions with Food and Herbs

Grapefruit:
  • Do not take grapefruit and its juice when you are on Buspirone.
  • This combination may raise Buspirone levels in the body and cause various adverse effects such as dizziness and sedation (1 Trusted Source
    Lilja, J. J., Kivistö, K. T., Backman, J. T., Lamberg, T. S., & Neuvonen, P. J. (1998). Grapefruit juice substantially increases plasma concentrations of buspirone. Clinical pharmacology and therapeutics, 64(6), 655–660.

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    ).

Buspirone Interactions with Alcohol

Avoid drinking alcohol while taking Buspirone because it can cause drowsiness, dizziness, an increased risk of overdose, difficulty breathing, impaired motor control, abnormal behavior and cognitive problems (2 Trusted Source
National Institute on Alcohol and Alcoholism. (2014) Harmful Interactions: Mixing Alcohol With Medicines

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).

When and How to Take Buspirone

  • Buspirone is available in the form of a tablet to be taken orally.
  • It is usually taken twice a day, with or without food.
  • Follow the directions exactly as given on the prescription label. Take the medication at the same time every day for better results.
  • Do not exceed or skip a dose. If you miss it, take the medication as soon as you remember.
  • Do not double the dose at a time to compensate for a missed dose (3 Trusted Source
    National Library of Medicine: Buspirone MedlinePlus Drug Information.

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    ).

References

1. Lilja, J. J., Kivisto, K. T., Backman, J. T., Lamberg, T. S., & Neuvonen, P. J. (1998). Grapefruit juice substantially increases plasma concentrations of buspirone. Clinical pharmacology and therapeutics, 64(6), 655-660. doi: 10.1016/S0009-9236(98)90056-X
2. National Institute on Alcohol and Alcoholism. (2014) Harmful Interactions: Mixing Alcohol With Medicines. https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/harmful-interactions-mixing-alcohol-with-medicines
3. National Library of Medicine: Buspirone MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a688005.html#

Drug Name : Buspirone

Buspirone is a psychoactive agent, prescribed for anxiety disorders.
We recommend consulting your doctor to verify the information presented on this page or if you need any further clarifications.


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