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Alendronate : Interaction with Foods, Herbs, Alcohol and Caffeine


Are you taking Alendronate? Are you aware of the dangers of combining Alendronate with certain foods, herbs or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.

Alendronate Interactions with Food and Herbs

Food:
  • Food may reduce Alendronate absorption, resulting in lower blood level of the medication and possibly reduced effectiveness.
  • It should be taken first thing in the morning, at least 30 minutes before you eat, drink, or take any other medications (1 Trusted Source
    Alendronate and Alcohol/Food Interactions

    Go to source
    ).

Orange Juice:
Avoid drinking orange juice with Alendronate, as it may decrease the oral absorption of the drug (2 Trusted Source
Food-Drug Interactions with Fruit Juices

Go to source
).

Multivitamins plus Minerals supplement:
When you are on Alendronate, avoid taking a multivitamin plus minerals supplement medication as it may interfere with the absorption of the drug into the bloodstream and reduce its potency (3 Trusted Source
Food And Drug Interaction

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).

Alendronate Interactions with Alcohol

While using Alendronate, avoid drinking alcohol as it may increase the risk of stomach adverse effects (3 Trusted Source
Food And Drug Interaction

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).

Alendronate Interactions with Caffeine

While taking Alendronate, it is better to avoid caffeine as it may reduce the drug's oral absorption (2 Trusted Source
Food-Drug Interactions with Fruit Juices

Go to source
).

When and How to Take Alendronate

  • Alendronate is available in the form of a tablet, an effervescent tablet and a solution (liquid) to be taken orally (by mouth).
  • The effervescent tablets and solution are usually taken on an empty stomach once a week in the morning.
  • Swallow the tablets as a whole instead of crushing, chewing or breaking them.
  • Follow the directions exactly as given on the prescription label.
  • Take the medication at the same time every day for better results.
  • Do not exceed or skip a dose. If you miss it, take the medication as soon as you remember.
  • Do not double the dose at a time to compensate for a missed dose (4 Trusted Source
    National Library of Medicine: Alendronate MedlinePlus Drug Information.

    Go to source
    ).

References

1. Alendronate and Alcohol/Food Interactions - https://www.drugs.com/food-interactions/alendronate.html?professional=1
2. Food?Drug Interactions with Fruit Juices
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823305/
3. Food And Drug Interaction
https://www.sefh.es/carpetasecretario/drug_food_herb_pamphlet.pdf
4. National Library of Medicine: Alendronate MedlinePlus Drug Information.
https://medlineplus.gov/druginfo/meds/a601011.html

Drug Name : Alendronate

Alendronate is used to treat or prevent osteoporosis or bone thinning in men and post-menopausal women and Paget's disease or bone deformity. It is also recommended for patients taking steroids that affect bone health. Alendronate is a bisphosphonate reduces the amount of calcium released from the bones into the blood.
We recommend consulting your doctor to verify the information presented on this page or if you need any further clarifications.


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Alendronate for Medical Condition(s)