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Drug information on Uropase (10 Lacs iu) (Urokinase) from Cadila Pharmaceuticals Ltd.

Uropase (10 Lacs iu)

Cadila Pharmaceuticals Ltd.
Generic : Urokinase
10 lacs iu/vial
1 Vial

Drug Name : Urokinase

Urokinase(Kinlytic) generic Uropase (10 Lacs iu) is an enzyme (thrombolytic agent), prescribed for deep vein thrombosis, heart attack, pulmonary embolism and peripheral vascular occlusion. It dissolves blood clots.
More Info about Urokinase

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Medical Condition(s) for which Uropase (10 Lacs iu) may be prescribed

Side effects of Uropase (10 Lacs iu)

•  Most Common: Severe bleeding.

•  Heart : Heart attack, recurrent blood clot in lungs, stroke.

•  Blood: Decreased red blood cells and platelets.

•  Miscellaneous: Excess sweating.

•  Potentially Fatal: Severe bleeding, severe allergic reactions, cholesterol embolization. Other side effects such as heart arrest and irregular heart rate have also been seen in patients taking urokinase.

Dosage & When it is to be taken (Indications)

Adult: IV- Deep vein thrombosis; Pulmonary embolism: Initial: 4,400 u/kg over 10 minutes, then 4,400 u/kg/hr for 12-24 hour (deep vein thrombosis) or 12 hour (pulmonary embolism).
Peripheral arterial thromboembolism: As 2,000 u/ml solution: Infuse into a clot via a catheter at a rate of 4,000 u/min for 2 hour.
Heart Attack: 2.5 lac IU over 10 minutes followed by 5 lac IU over the next 1 hour.

How to use Uropase (10 Lacs iu)?

It comes as a solution for injection to be injected by a healthcare provider into the vein.

When is Uropase (10 Lacs iu) not to be taken? (Contraindications)

Contraindicated in patients with active internal bleeding; history of stroke; recent (within 2 month) trauma including surgery on brain and spinal cord; aneurysm or tumor within the brain; known bleeding diathesis; severe uncontrolled high blood pressure, allergy to the drug.

Warnings and Precautions for Uropase (10 Lacs iu)

• Any vascular punctures or invasive procedures should be avoided.

•Caution needed for patients with history of peptic ulcer disease, pre-existing bleeding disorders, high blood pressure, heart infection, recent biopsy or surgery, recent injury, any allergies.

• Use extra caution to avoid injury and trauma. Use with caution in patients with liver or kidney disease, coagulation defects, brain disease, damage to the retina due to diabetes or any other condition in which bleeding could be dangerous, pregnancy or after recent surgery, childbirth or trauma.

•Monitor for reperfusion heart rate when used in heart attack.

•It may increase the risk of cerebral bleeding.

Other Precautions for Uropase (10 Lacs iu)

Blood tests including hematocrit, platelet count and activated partial thromboplastin time should be checked.

Storage Conditions for Uropase (10 Lacs iu)

Injection: Store below 25°C. Store it in room temperature, and in an airtight container.

Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Disclaimer : updates the prices regularly, however despite that there may be discrepancies in the prices displayed. This can be due to many reasons including -
  • Difference in GST/local taxes
  • Change in price by the company
  • Updation of information may not have happened at the right time
For the above reasons Medindia cannot be held liable for any action taken based on the information provided by its website. The purpose of this website is to only provide the initial guidance and it does not intend to replace professional medical opinion in any manner whatsoever.

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