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Drug information on Bactrim (100mg/20mg) (Sulphamethoxazole 100mg + Trimethoprim 20mg) from AHPL

Bactrim (100mg/20mg)

  Pediatric Tablet
AHPL
Generic : Trimethoprim
 2.58
100mg/20mg
10
Combination of Generics : Sulphamethoxazole 100mg + Trimethoprim 20mg
Vijayaganesh Kasinathan
Written & Compiled by Pharmacist Vijayaganesh Kasinathan, B.Pharm, M.Pharm
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Sep 23, 2017
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Side effects of Trimethoprim

  Skin: Rashes, itching, photosensitivity (sensitivity of the skin to sunlight), rarely serious skin reactions like Stevens Johnson syndrome and epidermal necrolysis.

  Gastrointestinal System: Nausea, vomiting, glossitis and gastrointestinal discomfort, diarrhea.

  Liver: Alterations in liver enzymes, cholestatic jaundice (rare).

  Blood: Reduced blood counts, megaloblastic anemia.

  Others: Muscle aches, headache, fever, aseptic meningitis, increased serum creatinine and blood urea nitrogen levels (which could indicate reduced kidney function).

When is Trimethoprim not to be taken? (Contraindications)

Trimethoprim is contraindicated in the following conditions:
• Patients with megaloblastic anemia. Megaloblastic anemia occurs due to folic acid deficiency. Therefore, trimethoprim can worsen the condition.
• Pregnancy, especially in the first trimester due to its interference with folic acid metabolism. Adequate supplementation should be provided in case it is unavoidable.
• Patients allergic to the drug.




Disclaimer : Change in the rate of medication is possible and the rates shown maybe more or less than the rate displayed due to added GST and pricing changes made by the companies.
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