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Drug information on Melalite-XL (Tretinoin) from AHPL

Melalite-XL

  Cream
AHPL
Generic : Tretinoin
 129.66
2% w / w / 0.025% w / w / 0.1% w / w
15g
Written & Compiled by Anushta Chandrapalan, M.Sc Biotechnology | Medically Reviewed by The Medindia Medical Review Team on February, 2, 2017
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Medical Condition(s) for which Melalite-XL may be prescribed


Side effects of Melalite-XL

   Most Common : Headache, fever, skin dryness, bone pain, nausea/vomiting, rash, itching, increased sweating, visual disturbances, hair loss, skin changes and bone inflammation.

   Body as a Whole : Uneasiness, shivering, bleeding, infections, swelling in the extremities, chest discomfort, increased and decreased weight, injection site reactions, loss of appetite, muscle pain, flank pain, fluid imbalance, pallor, lymph disorders, acidity and chills.

   Respiratory : Upper respiratory tract disorders, difficulty in breathing, respiratory insufficiency, pneumonia, wheezing, lung infection/swelling and asthma.

   ENT : Ear pain and hearing loss.

   Gastrointestinal : GI hemorrhage, abdominal pain, diarrhea, constipation, indigestion, abdominal distention, liver inflammation, ulcer and unspecified liver disorder.

   Heart : Abnormal heart rate, flushing, low/high blood pressure, vein inflammation, heart failure, heart attack, enlarged heart, heart murmur and stroke.

   Central Nervous System : Dizziness, tingling, anxiety, sleeplessness, depression, confusion, agitation, hallucinations, abnormal gait, convulsions, coma, CNS depression, speech disorder, encephalopathy, facial paralysis, tremor, leg weakness, unconsciousness, dementia, memory loss, drowsiness and slow speech.

   Genitourinary : Kidney impairment, painful urination, urinary frequency and enlarged prostate.

   Miscellaneous : Skin lesions.

Dosage & When it is to be taken (Indications)

PO- The recommended dose is 45 mg/m2/day administered as two evenly divided doses.
Topical- 0.05% apply a thin layer of cream over the affected area.

How to use Melalite-XL?

It comes as a capsule to take by mouth, with or without food.
Topical- It comes as a liquid, cream and gel to apply topically.

When is Melalite-XL not to be taken? (Contraindications)

Hypersensitivity.

Warnings and Precautions for Melalite-XL

Caution should be exercised in patients with history of blood cholesterol, liver or heart disease, abnormally high white blood cell count, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
It may cause dizziness or severe headache, do not drive a car or operate machinery while taking this medication.
Monitor pregnancy tests, blood clotting factors, blood cholesterol and triglyceride levels, liver function and white blood cell counts regularly while taking this medication.
It should not be used in children less than 1 year old.
Topical :
Wash your hands thoroughly after applying this medication.
Avoid exposure to sunlight.
Keep away from eyes, mouth, angles of nose, mucous membranes or open wounds.

Other Precautions for Melalite-XL

Avoid excess dosage.

Storage Conditions for Melalite-XL

Store at 15° to 30°C. Keep the container tightly closed at room temperature and out of the reach of children.


Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.



Disclaimer : Change in the rate of medication is possible and the rates shown maybe more or less than the rate displayed due to added GST and pricing changes made by the companies.
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