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Drug information on Rapacan (Sirolimus) from Biocon Limited


Biocon Limited
Generic : Sirolimus
Written & Compiled by Anushta Chandrapalan, M.Sc Biotechnology | Medically Reviewed by The Medindia Medical Review Team on February, 2, 2017
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Medical Condition(s) for which Rapacan may be prescribed

Side effects of Rapacan

   Most Common : Swelling in the extremities, high blood pressure, increased cholesterol level, constipation, abdominal pain, diarrhea, headache, fever, urinary tract infection, anemia, nausea, joint pain, and decrease in platelet counts.

   Body as a Whole : Sepsis and infections.

   Heart : Blood clot events and fast heart rate.

   Gastrointestinal : Mouth ulcer.

  Metabolic: Abnormal healing, increased level of lactic dehydrogenase (LDH) and decrease in blood potassium level.

   Musculoskeletal : Death of bone cells.

   Respiratory : Nose bleed and lung infection.

   Skin : Skin cancer and rash.

   Genitourinary : Kidney inflammation.

Dosage & When it is to be taken (Indications)

Adult: PO- Low-moderate risk patients: 6 mg on day 1. Maintenance: 2 mg once daily, given 4 hour after ciclosporin.
High immunological risk patients: Recommended loading dose: 15 mg. Maintenance: 5 mg/day.

How to use Rapacan?

It comes as a tablet to take by mouth, on an empty stomach or with food.

When is Rapacan not to be taken? (Contraindications)


Warnings and Precautions for Rapacan

Caution should be exercised in patients with history of liver, kidney problems, high cholesterol, low blood platelet levels, diabetes, lung or breathing problems, any allergy, infections, who are taking other medications especially for HIV or Hepatitis C , during pregnancy and breastfeeding.

• Avoid contact with people who have infections.

• Patient may develop with increased risk of progressive multifocal leukoencephalopathy (PML), severe kidney problems, certain types of cancer; if it is so consult with your doctor.

• Avoid live vaccination while taking this medication.

• It may affect blood sugar level; monitor sugar level regularly while taking this medication.

Other Precautions for Rapacan

Avoid excess dosage.

Storage Conditions for Rapacan

Store it at room temperature (25°C), and in an airtight container.

♦ Safety Labeling Changes Approved By FDA

Disclaimer : Change in the rate of medication is possible and the rates shown maybe more or less than the rate displayed due to added GST and pricing changes made by the companies.
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Substitutes for Rapacan

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