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Drug information on Rapacan (Sirolimus) from Biocon Limited


Biocon Limited
Generic : Sirolimus
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Drug Name : Sirolimus

Sirolimus(Rapamune) generic Rapacan is an immunosuppressant, prescribed for preventing rejection of kidney transplants either alone or with other medications. It works by suppressing the body's immune system.
More Info about Sirolimus

Other Trade Names for Sirolimus

India : 

International : 

Rapamune, Siromus, Rapacan
Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team on February, 2, 2017

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Medical Condition(s) for which Rapacan may be prescribed

Side effects of Rapacan

   Most Common : Swelling in the extremities, high blood pressure, increased cholesterol level, constipation, abdominal pain, diarrhea, headache, fever, urinary tract infection, anemia, nausea, joint pain, and decrease in platelet counts.

   Body as a Whole : Sepsis and infections.

   Heart : Blood clot events and fast heart rate.

   Gastrointestinal : Mouth ulcer.

  Metabolic: Abnormal healing, increased level of lactic dehydrogenase (LDH) and decrease in blood potassium level.

   Musculoskeletal : Death of bone cells.

   Respiratory : Nose bleed and lung infection.

   Skin : Skin cancer and rash.

   Genitourinary : Kidney inflammation.

Dosage & When it is to be taken (Indications)

Adult: PO- Low-moderate risk patients: 6 mg on day 1. Maintenance: 2 mg once daily, given 4 hour after ciclosporin.
High immunological risk patients: Recommended loading dose: 15 mg. Maintenance: 5 mg/day.

How to use Rapacan?

It comes as a tablet to take by mouth, on an empty stomach or with food.

When is Rapacan not to be taken? (Contraindications)


Warnings and Precautions for Rapacan

Caution should be exercised in patients with history of liver, kidney problems, high cholesterol, low blood platelet levels, diabetes, lung or breathing problems, any allergy, infections, who are taking other medications especially for HIV or Hepatitis C , during pregnancy and breastfeeding.

• Avoid contact with people who have infections.

• Patient may develop with increased risk of progressive multifocal leukoencephalopathy (PML), severe kidney problems, certain types of cancer; if it is so consult with your doctor.

• Avoid live vaccination while taking this medication.

• It may affect blood sugar level; monitor sugar level regularly while taking this medication.

Other Precautions for Rapacan

Avoid excess dosage.

Storage Conditions for Rapacan

Store it at room temperature (25°C), and in an airtight container.

♦ Safety Labeling Changes Approved By FDA

Disclaimer : updates the prices regularly, however despite that there may be discrepancies in the prices displayed. This can be due to many reasons including -
  • Difference in GST/local taxes
  • Change in price by the company
  • Updation of information may not have happened at the right time
For the above reasons Medindia cannot be held liable for any action taken based on the information provided by its website. The purpose of this website is to only provide the initial guidance and it does not intend to replace professional medical opinion in any manner whatsoever.

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