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Drug information on Pirfenex (200mg) (Pirfenidone 20mg) from Cipla Limited

Pirfenex (200mg)

  Film coated tablet
Cipla Limited
Generic : Pirfenidone
 160.00
200mg
10
Combination of Generics : Pirfenidone 20mg

Drug Name : Pirfenidone

Pirfenidone generic Pirfenidone is prescribed for treating idiopathic pulmonary fibrosis which is a severe irreversible disease marked by a progressive decline in lung function. The scarring of lungs is caused by some unknown origin. The exact mechanism of action of pirfenidone is not known. Pirfenidone is thought to reduce the lung fibrosis (scarring and thickening of lungs) by decreasing the release or activity of naturally occurring substances in the body such as certain growth factors.
More Info about Pirfenidone


Vijayaganesh Kasinathan
Written & Compiled by Pharmacist Vijayaganesh Kasinathan, B.Pharm, M.Pharm
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Sep 28, 2017
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Side effects of Pirfenidone

  Gastrointestinal: Nausea, vomiting, gastritis, GERD (gastro oesophageal reflux disease), loss of appetite, indigestion, abdominal pain, abdominal distension

  Skin: Photosensitivity, rash, itching and dry skin

  Central Nervous System: Dizziness, insomnia, and fatigue

  Respiratory: Sinusitis and upper respiratory infections

  Others: Increased liver enzymes, joint pain, weight loss

When is Pirfenidone not to be taken? (Contraindications)

Pirfenidone is not recommended in patients with:

• End stage renal disease who require dialysis.
• Severe liver impairment or damage.

It is also contraindicated in patients taking fluvoxamine treatment.




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