Phenylephrine (Coryzia) is a selective alpha agonist, used to increase blood pressure and topically as a nasal decongestant. It is also used in the eye to dilate the pupil or to constrict superficial blood vessels in eye allergy. It works by reducing swelling of the blood vessels in the nasal passages.
The information provided on this page is intended to serve as a comprehensive resource and should not be a substitute to professional medical advice. If you have concerns it is always best to speak with a healthcare professional.
The recommended dose is: IM- 2 to 5 mg. IV- 0.1 to 0.5mg by slow infusion. PO- 5 to 10mg. Nasal- Nasal congestion: As 0.25-1% solution: Instill/spray 4 hourly as needed. Ophthalmic- Usually 0.12% solution: Instill 1-2 drops â‰¤4 times/day for â‰¤72 hour.
What are the common side effects of Coryzia
Skin: Hives, itching, rash, photosensitivity.
Heart: High blood pressure, abnormal heart rhythm.
Central Nervous System : Tremor, irritability, sleeplessness, weakness, nervousness, headache.
EYE: Blurring of vision, stinging or burning sensation in the eye due to eye drops.
Respiratory : Tightness of the chest and wheezing, shortness of breath.
How to use Coryzia?
It comes as a tablet, a liquid, or a dissolving strip to take by mouth. It is also comes as eye drops and nasal solution, instilled over affected area.
In which conditions should Coryzia be avoided?
Contraindicated in patients with increased blood pressure, increase in heart rate, raised eye pressure. It should not be used with a MAO inhibitor.
What are the Precautions needed with Coryzia
Do not give phenylephrine containing products to children younger than 4 years of age. It may cause serious side effects or cause of death in children.
Do not use this medication for longer duration, it may cause rebound congestion in prolonged or excessive use of nasal or eye drops.
Caution should be exercised in patients with history of severe increase in thyroid hormone, severe heart disease, diabetes, prostate enlargement, during pregnancy and breastfeeding.
Are there any additional Precautions?
Instill properly as directed by your physician.
At What Temperature Should it be Stored?
Refer to the package insert. Some products are stored at room temperature whereas some are stored under refrigeration.
A: Coryzia is a safe and effective drug. But, it may cause side effects like nausea, vomiting, headache, fatigue, dizziness, dry mouth, sleepiness, and an allergic reaction in some patients (1✔✔Trusted Source Phenylephrine
A: Yes, Coryzia nasal spray is available and is used to relieve nasal discomfort caused by colds and allergies. It is usually taken every 4 hours to relieve the symptoms. Coryzia nasal spray is intended only for use in the nose (3✔✔Trusted Source Phenylephrine Nasal Spray
A: Coryzia when taken orally has a minimal direct effect on heart rate. But, at higher doses, these medications can increase systolic and diastolic blood pressure and cause reflex bradycardia (4✔✔Trusted Source Phenylephrine : Sciencedirect
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