Nebivolol is a beta-blocker, prescribed for hypertension either alone or combined with other medications. It is also used for some cases of heart failure. It decreases the amount of blood pumped out from heart. This helps to decrease blood pressure and reduces the workload on the heart. 

Drug information on Nebi (Nebivolol) from Aristo Pharmaceuticals Pvt. Ltd.


Aristo Pharmaceuticals Pvt. Ltd.
Generic : Nebivolol
10 Tablets
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Medical Condition(s) for which Nebi may be prescribed

Benefits of Blood Pressure Tablets on your Health
Diabetes and Hypertension
High Blood Pressure
Mitral Valve Prolapse

Side effects of Nebi

  Heart: Slow heart rate, heart failure, low blood pressure .

   Gastrointestinal: Diarrhea, nausea, abdominal pain,constipation.

  Central Nervous System: Headache, dizziness, sleeplessness, weakness, tingling.

  Respiratory: Wheezing, cough, nasopharyngitis (inflammation of nose and throat).

  Skin: Rash.

  Metabolic: Increased level of cholesterol, and uric acid in the blood.

Others: fatigue, peripheral edema, joint pain, rash

Dosage & When it is to be taken (Indications)

Hypertension- 5 to 40mg once daily.
Heart failure: 1.25-10 mg once daily.

How to use Nebi?

It comes as a tablet to take by mouth, with or without food once a day.

When is Nebi not to be taken? (Contraindications)

Nebivolol should not be used in patients allergic to the drug, with slow heartbeat, low cardiac output, or liver failure

Warnings and Precautions for Nebi

Avoid abrupt withdrawal of the drug.
The drug should be used with caution if the patient is having any of these conditions:
• Occasional numbness and tingling in the fingers. • Asthma.
• Chronic obstructive pulmonary disease (COPD).
• Diabetes, since it may mask the effects of low blood sugar levels.
• Hyperthyroidism, or high thyroid hormone levels.
• Kidney or liver function problems. These patients are started with a low dose.
• Skin condition called psoriasis.
• Untreated pheochromocytoma, which is a tumor of the adrenal gland.
• Metabolic acidosis like diabetic ketoacidosis.

Other Precautions for Nebi

Avoid excess dosage.
Nebivolol may cause dizziness, do not drive a car or operate machinery while taking this medication.

Drug Interactions of Nebi

Nebivolol should be avoided with:
• Other beta blockers due to additive effects.
• Other drugs with depressant effects on the heart including calcium channel blockers like amlodipine, verapamil and diltiazem, heart failure drugs digoxin or digitoxin, and drugs that normalize heart rhythm like quinidine, disopyramide, flecainide, and mexiletine. Combination with some of these drugs may be necessary in cases that cannot be controlled with a single drug.
• Antidiabetic drugs since nebivolol can block the signs and of low blood sugar levels.
• Drugs that inhibit CYP2D6 enzyme like paroxetine, fluoxetine and thioridazine, which can increase nebivolol level in the blood resulting in reduced heart rate.
• Drugs used in the treatment of asthma due to opposite effects on the bronchi.
• Non-steroidal anti-inflammatory drugs like ibuprofen and diclofenac which may block the action of nebivolol on blood pressure.
• Other drugs which reduce blood pressure due to additive effect.
• Antipsychotics like phenothiazines, barbiturates and tricyclic antidepressants due to excessive reduction in heart rate.

Storage Conditions for Nebi

Oral: Store it at room temperature (20-25°C) and in an airtight container.Protect from excess heat and moisture. Keep out of reach of children.

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Disclaimer : The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including local taxes. These are only approximate indicative prices of the drug.
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