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Drug information on Orahex-M (Metronidazole) from AHPL

Orahex-M   Ointment    AHPL Generic : Metronidazole	30.45 10mg/0.25% W/W 20 g

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Abdominal Pain

Amoebic Dysentery

Animal Bites

Anosmia

Appendicitis

Balantidiasis

Diverticulosis and Diverticulitis

Infective Endocarditis

•   Most common : Headache, loss of appetite, vomiting, diarrhea and abdominal cramping.

•   Blood : Decrease in white blood cells and platelets.

•   Heart : ECG changes.

•   Central Nervous System : Brain disease, seizures, eye nerve problems, dizziness, unsteadiness, in coordination, confusion, irritability, depression, weakness and sleeplessness.

•   Hypersensitivity : Hives, rash, Stevens-Johnson syndrome, skin death, flushing, nasal congestion, dryness of the mouth and fever.

•   Genitourinary : Painful urination, bladder inflammation, adequate urination and incontinence.

PO- One-day treatment - two grams of flagyl, given either as a single dose or in two divided doses of one gram each given in the same day.
Seven-day course of treatment�250 mg three times daily for seven consecutive days.
Vaginal Gel- one applicator is administered intravaginally once a day for 5 days.

It comes as a tablet to take by mouth, with or without food. It also comes as vaginal gel, to be introduced into the vagina.

Hypersensitivity.

• Caution should be exercised in patients with history of nerve, brain, Crohn�s disease, liver impairment, seizures, heart disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Avoid long-term use of this medication; otherwise it may cause secondary infection.

Avoid excess dosage.

Store this medication at room temperature, out of reach of children.