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Drug information on Alkeran (5mg) (Melphalan) from Glaxo SmithKline Pharmaceuticals Ltd.

Alkeran (5mg)

  Tablet  
Glaxo SmithKline Pharmaceuticals Ltd.
Generic : Melphalan
 337.89
5mg
25
Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team on February, 2, 2017
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Medical Condition(s) for which Alkeran (5mg) may be prescribed


Side effects of Alkeran (5mg)

   Most common : Bone marrow suppression.

   Gastrointestinal : Nausea, vomiting, diarrhea and oral ulceration.

   Liver : Abnormal liver function, jaundice and liver inflammation.

   Miscellaneous : Lung scar, lung inflammation, skin hypersensitivity, rash, inflammation of blood vessels, hair loss and anemia.

   Allergic reactions : Hives, swelling, and rarely shock.

Dosage & When it is to be taken (Indications)

PO- Multiple Myeloma: The usual oral dose is 6 mg (3 tablets) daily. The entire daily dose may be given at one time.
Epithelial Ovarian Cancer: dose of 0.2 mg/kg daily for 5 days as a single course. Melanoma: 0.6-1 mg/kg.

How to use Alkeran (5mg)?

It comes as a tablet to take by mouth, on an empty stomach. It also comes as a solution for injection to be administered by a healthcare provider into the vein.

When is Alkeran (5mg) not to be taken? (Contraindications)

Contraindicated in patients with severe bone marrow suppression and hypersensitivity.

Warnings and Precautions for Alkeran (5mg)

Caution should be exercised in patients with history of bone marrow depression, infection, low white blood cell count, kidney problems, shingles, chickenpox, under going radiation therapy, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

• Avoid contact with people who have infections.

• It may affect platelet counts; to prevent bleeding avoid injury or bruising.

• Monitor complete blood counts regularly while taking this medication.

Other Precautions for Alkeran (5mg)

Avoid excess dosage.

Storage Conditions for Alkeran (5mg)

Store it in the refrigerator (2° to 8°C), and keep away from children.



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