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Drug information on Dotra-M (80mg/250mg) (Drotaverine 80mg+ Mefenamic acid 250mg) from Emcure Pharmaceuticals Ltd (Shweiz)

Dotra-M (80mg/250mg)   Film coated tablet Emcure Pharmaceuticals Ltd (Shweiz) Generic : Mefenamic acid	62.50 80mg/250mg 10
Combination of Generics : Drotaverine 80mg+ Mefenamic acid 250mg

•   Gastrointestinal : Abdominal pain, constipation, diarrhea, indigestion, flatulence, gross bleeding/perforation, gastric/peptic ulcers, heartburn, nausea, mouth ulcer, GI ulcers, vomiting, anemia, elevated liver enzymes, and blood vomiting.

•   Body as a whole : Fever, infection and sepsis.

•   Heart : Heart failure, high blood pressure, fast heart rate and fainting.

•   Liver : Liver inflammation and jaundice.

•   Blood : Eosinophilia, decrease in white blood cells, bruising, blood in stool and rectal bleeding.

•   Metabolic : Weight changes.

•   Central Nervous system : Anxiety, weakness, confusion, depression, dream abnormalities, drowsiness, dizziness, sleeplessness, uneasiness, headache, nervousness, tingling and tremors.

•   Respiratory : Asthma and difficulty in breathing.

•   Skin : Hair loss, sensitivity to light, itching and increased sweating.

•   Eye and ENT : Blurred vision and ringing in the ear.

•   Genitourinary : Bladder inflammation, painful urination, blood in urine and kidney failure.

Contraindicated in patients who have experienced asthma, hives, allergic reactions after taking aspirin or other NSAIDs, peri-operative pain, ulcer, kidney disease and hypersensitivity.

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