Mannitol (Mannitol IV) is an osmotic diuretic, prescribed for increased intracranial pressure, eye pressure, to maintain urine flow in kidney failure patients, and promotion of urinary excretion of toxic materials.
Nausea, vomiting, runny nose, local pain, chills, dizziness, hives and chest pain.
How to use Mannitol IV?
It comes as a solution for injection to be administered by a healthcare provider into the vein.
When Should Mannitol IV not be taken? (Contraindications)
Contraindicated in patients with heart failure, stroke, anuria, severe dehydration, and hypersensitivity.
Warnings and Precautions for Mannitol IV
Caution should be exercised in patients with history of swelling, kidney problems, or heart problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Monitor blood electrolytes, kidney function, lung function, heart function, and blood counts regularly while taking this medication.
Other Precautions for Mannitol IV
Avoid excess dosage.
Storage Conditions for Mannitol IV
Store it at controlled room temperature (15° to 30°C), and in an airtight container.
A: Mannitol IV is harmful to the kidneys and should be used with caution. A high dose of Mannitol IV may cause nephrotoxicity (kidney damage), especially in patients with renal insufficiency (2✔✔Trusted Source Incidence and Risk Factors for Acute Kidney Injury Following Mannitol Infusion in Patients With Acute Stroke
A: Mannitol IV should be administered only by intravenous (IV) infusion rather than oral administration because it is rapidly excreted in IV infusion and poorly absorbed in oral administration (1✔✔Trusted Source Mannitol
A: Yes, Mannitol IV is a diuretic (water pill) given to increase urine output. It is generally given to evaluate the kidney's functions. When prescribed at night, it is advised to take this medication in the early evening to avoid frequent wake-ups to urinate (3✔✔Trusted Source Mannitol increases renal blood flow and maintains filtration fraction and oxygenation in postoperative acute kidney injury: a prospective interventional study
A: When administered at high concentrations, Mannitol IV may cause excessive expansion of the intravascular space, which may result in congestive heart failure and pulmonary edema (1✔✔Trusted Source Mannitol
2. Incidence and Risk Factors for Acute Kidney Injury Following Mannitol Infusion in Patients With Acute Stroke - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058971/ )
3. Mannitol increases renal blood flow and maintains filtration fraction and oxygenation in postoperative acute kidney injury: a prospective interventional study - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580749/ )
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