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Drug information on M-Cal 250 (Magnesium Sulphate) from Stedman Pharmaceuticals Pvt. Ltd.

M-Cal 250

  Film coated tablet
Stedman Pharmaceuticals Pvt. Ltd.
Generic : Magnesium Sulphate
 150.00
625mg/200IU/100mg
15
Pallavi Singh
Written & Compiled by Pharmacist Pallavi Singh, M. Pharmacy (Pharmacy Practice)
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Jan 18, 2018
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Medical Condition(s) for which M-Cal 250 may be prescribed


Overview of M-Cal 250

• Magnesium sulphate is important for muscles and nerves.
• It is also used as a laxative for constipation and to prevent and treat seizures in pre-eclampsia and eclampsia.

Side effects of M-Cal 250

  Digestive tract: Mild cramps, after constipation after taking laxative, diarrhea, stomach irritation, nausea, vomiting, paralytic ileus

  Nervous system: Confusion, dizziness or lightheadedness, sleepiness, slurred speech, double vision, muscle weakness

  Cardiovascular system: Fast, slow, or irregular heartbeat, low blood pressure

  Skin: Skin infection after local application

  Others: Allergic reaction

Dosage & When it is to be taken (Indications)

• The dosage and route of administration varies according to the condition for which magnesium sulphate is used, and the route of administration.

• The maintenance dose should be adjusted according to the response noted.

How to use M-Cal 250?

• Depending on the dosage form, magnesium sulphate is taken orally, injected into the muscle or a vein, or applied on the skin.

When is M-Cal 250 not to be taken? (Contraindications)

Magnesium sulphate is contraindicated in patients with:

• Allergy to the drug
Kidney disease
• Heart disease like heart block or heart muscle damage, or patients on digoxin treatment
Myasthenia gravis
• Severe nausea, vomiting, perforation of bowel, bowel obstruction, sudden changes in bowel habits (for magnesium sulphate laxative)

Warnings and Precautions for M-Cal 250

• Monitor kidney function, blood pressure and respiratory rate regularly during treatment with magnesium sulphate.
• Oral magnesium sulphate should not be used in pregnancy.

Other Precautions for M-Cal 250

• Take magnesium sulphate only as advised by the physician.

Drug Interactions of M-Cal 250

• Magnesium sulphate when it is combined with drugs that include tetracycline antibiotics like demeclocycline, doxycycline and minocycline, and biphosphonates decreases their absorption from the digestive tract.
• Magnesium sulphate causes additional neuromuscular blocking effect with drugs like aminoglycosides, and nifedipine and nimodipine.

• Magnesium sulphate may increase drowsiness caused by other drugs with sedative effects.
• It should not be used in patients taking digoxin for heart disease.

Storage Conditions for M-Cal 250

• Magnesium sulphate should be stored at room temperature of 20°C to 25°C.



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