Enerzal LiqdOral LiquidFDC Limited (Proxima) Generic : Magnesium Sulphate | ![]() |
• Magnesium sulphate is important for muscles and nerves.
• It is also used as a laxative for constipation
and to prevent and treat seizures in pre-eclampsia and eclampsia.
• Digestive tract: Mild cramps, after constipation after taking laxative, diarrhea, stomach irritation, nausea, vomiting, paralytic ileus
• Nervous system: Confusion, dizziness or lightheadedness, sleepiness, slurred speech, double vision, muscle weakness
• Cardiovascular system: Fast, slow, or irregular heartbeat, low blood pressure
• Skin: Skin infection after local application
• Others: Allergic reaction
• The dosage and route of administration varies according to the condition for which magnesium sulphate is used, and the route of administration.
• The maintenance dose should be adjusted according to the response noted.
• Depending on the dosage form, magnesium sulphate is taken orally, injected into the muscle or a vein, or applied on the skin.
Magnesium sulphate is contraindicated in patients with:
• Allergy to the drug
• Kidney disease
• Heart disease like heart block or heart muscle damage, or patients on digoxin treatment
• Myasthenia gravis
• Severe nausea, vomiting, perforation of bowel, bowel obstruction, sudden changes in bowel habits (for magnesium sulphate laxative)
• Monitor kidney function, blood pressure and respiratory rate regularly during treatment with magnesium sulphate.
• Oral magnesium sulphate should not be used in pregnancy.
• Take magnesium sulphate only as advised by the physician.
• Magnesium sulphate when it is combined with drugs that include tetracycline antibiotics like demeclocycline, doxycycline and minocycline, and biphosphonates decreases their absorption from the digestive tract.
• Magnesium sulphate causes additional neuromuscular blocking effect with drugs like aminoglycosides, and nifedipine and nimodipine.
• Magnesium sulphate may increase drowsiness caused by other drugs with sedative effects.
• It should not be used in patients taking digoxin for heart disease.
• Magnesium sulphate should be stored at room temperature of 20°C to 25°C.