Levesam (Levetiracetam) Drug Price and Information

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PO/IV- Adjunct in partial seizures- Initial: 500 mg twice daily on the 1st day, may increase gradually. Max: 3 g/day.
Monotherapy for partial seizures with or without secondary generalization- Initial: 500 mg/day, may increase gradually. Max: 3 g/day.

Central Nervous System: Drowsiness, weakness, headache, hostility, fatigue, nervousness, dizziness, personality disorder, irritability, agitation, emotional lability, depression, mood swings, vertigo, anxiety, unsteadiness, seizures, memory loss, confusion, increased reflexes, tingling, aggression and suicidal behavior.

Skin: Itching, skin discoloration, rash and loss of hair.

Eye and ENT: Inflammation of nasopharynx, stuffy nose, inflammation of conjunctiva, blurred vision, double vision and ear pain.

Gastrointestinal: Vomiting, loss of appetite, diarrhea, nausea, gastroenteritis, constipation and inflammation of pancreas.

Genitourinary: Albumin in urine and urine abnormality.

Blood: Easy bruising, deficiency of all three blood cell types (with bone marrow suppression in some cases).

Liver: Abnormal LFTs (liver function test), liver failure and inflammation.

Metabolic: Dehydration and weight loss.

Musculoskeletal: Neck pain.

Respiratory: Increased cough, asthma and sinusitis.

Miscellaneous:Accidental injury, infection, influenza, pain, flu syndrome, face edema and viral infection.

May be taken with or without food. (Oral solution should be diluted in a glass of water.) Administer IV levetiracetam as 15-min infusion following dilution in 100 ml of a compatible diluent.

Hypersensitivity.

Caution should be exercised in patients with history of liver or kidney problems, allergic reactions, patients undergoing haemodialysis, pregnancy and breastfeeding.

Patient may develop mood changes, suicidal thoughts.

It may impair ability to drive or operate machinery during initial therapy.

Do not change the dosage.

Intravenous: Once reconstituted store at 15-30°C and use within 24 hr. Store tablets, oral solution, and undiluted IV injection at 15-30°C.