Name: Durea
Creator: Anushta Chandrapalan

Durea is an antineoplastic agent, prescribed for sickle cell anemia, several types of cancer (such as melanoma, chronic myelogenous leukemia, squamous cell carcinomas), as an adjunct to antiretroviral therapy for AIDS. It is also used for psoriasis.

Durea Capsule/ Tablet Samarth Pharma Pvt. Ltd. Generic : Hydroxyurea	₹ 307.20 500mg 4 x 6

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Drug information on Durea (Hydroxyurea) from Samarth Pharma Pvt. Ltd.

Drug Name : Hydroxyurea

Hydroxyurea(Droxia) generic Durea is an antineoplastic agent, prescribed for sickle cell anemia, several types of cancer (such as melanoma, chronic myelogenous leukemia, squamous cell carcinomas), as an adjunct to antiretroviral therapy for AIDS. It is also used for psoriasis.
More Info about Hydroxyurea

Written & Compiled by Anushta Chandrapalan, M.Sc | Medically Reviewed by The Medindia Medical Review Team on February, 2, 2017

Medical condition(s) for which Durea may be prescribed

Dosage & When it is to be taken (Indications)

Intermittent Therapy
80 mg/kg administered orally as a single dose every third day.
Continuous Therapy
20 to 30 mg/kg administered orally as a single dose daily.
Concomitant Therapy with Irradiation
Carcinoma of the head and neck—80 mg/kg administered orally as a single dose every third day.

Side effects of Durea

Most common : Bone marrow depression.

Gastrointestinal : Mouth ulcer, loss of appetite, nausea, vomiting, diarrhea and constipation.

Skin : Rash, skin ulceration, skin changes and redness.

How to use Durea?

It comes as a capsule and tablet to take by mouth, with or without food.

When Should Durea not be taken? (Contraindications)

Contraindicated in patients with severe bone marrow depression, abnormal decrease in blood cell counts and hypersensitivity.

Warnings and Precautions for Durea

Caution should be exercised in patients with history of AIDS, who have undergone radiation therapy, liver or kidney disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may reduce platelet counts; avoid injury or bruising.

It may be harmful if it gets on the skin; avoid direct contact with hands.

Avoid vaccination while taking this medication.

Other Precautions for Durea

Avoid drinking alcoholic beverages and citrus juices.
Avoid excess dosage.

Storage Conditions for Durea

Keep it out of reach of children in a safe place.

Schedule : G Drugs that are to be used only under medical supervision.

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