A: Glyree is safe, effective in diabetic patients with renal impairment. Patients with mild to severe kidney disease can take Glyree, but they should start slowly and gradually increase the dose (3✔✔Trusted Source Pharmacokinetics and safety of glimepiride at clinically effective doses in diabetic patients with renal impairment
A: Glyree may cause weight gain. Sulfonylureas drugs commonly used to treat diabetes are associated with weight gain. Glyree should be used in combination with a healthy diet and regular exercise to help control weight gain (2✔✔Trusted Source Glimepiride
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3. Pharmacokinetics and safety of glimepiride at clinically effective doses in diabetic patients with renal impairment - (https://pubmed.ncbi.nlm.nih.gov/8960852/#:)
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