Gliclazide (Glynol -M) is an oral hypoglycemic (anti-diabetic drug), prescribed for type 2 diabetes. It stimulates the pancreas, which helps in more insulin secretion.
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Q: What happens if Glynol -M is taken on an empty stomach?
A: Glynol -M should be taken 30 minutes before breakfast. Glynol -M promotes more appropriate insulin release and better glucose disposition when taken 30 minutes before breakfast than when taken with breakfast(1✔✔Trusted Source Influence of food intake on the absorption and effect of glipizide in diabetics and in healthy subjects
A: Sulfonylureas have been linked to an increased risk of drug-induced idiosyncratic liver disease. A diabetic patient developed acute icteric liver necro-inflammation after starting Glynol -M therapy(2✔✔Trusted Source Gliclazide-induced acute hepatitis
A: Glynol -M not only has a hypoglycemic action but also possesses antiplatelet activity by inhibiting platelet aggregation via the serotonin pathway(3✔✔Trusted Source Effects of gliclazide on platelet aggregation and the plasminogen activator inhibitor type 1 level in patients with type 2 diabetes mellitus
A: The use of oral diabetes medications during pregnancy is not advised due to known adverse effects on the fetus, such as congenital abnormalities, fetal hyperinsulinemia, and neonatal hypoglycemia(4✔✔Trusted Source Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy
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1. Influence of food intake on the absorption and effect of glipizide in diabetics and in healthy subjects - (https://pubmed.ncbi.nlm.nih.gov/7002565/)
3. Effects of gliclazide on platelet aggregation and the plasminogen activator inhibitor type 1 level in patients with type 2 diabetes mellitus - (https://pubmed.ncbi.nlm.nih.gov/20070990/#:)
4. Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy - (https://pubmed.ncbi.nlm.nih.gov/19109210/)
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