Gliclazide (Glim C) is an oral hypoglycemic (anti-diabetic drug), prescribed for type 2 diabetes. It stimulates the pancreas, which helps in more insulin secretion.
PO- Initially start with 160mgs daily in two divided doses. May go up to 320 mgs daily in two divided doses.
What are the common side effects of Glim C
GI disturbances, skin reaction, decrease in blood cell counts, jaundice, vomiting, diarrhea and stomach inflammation.
How to use Glim C?
It comes as a tablet to take by mouth, with food.
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In which conditions should Glim C be avoided?
Contraindicated in patients with diabetic-ketoacidosis, severe liver and kidney impairment, and hypersensitivity.
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What are the Precautions needed with Glim C
Caution should be exercised in patients with history of liver, kidney problems, any allergy, during pregnancy and breastfeeding.
Monitor bloodsugar level regularly while taking this medication.
Are there any additional Precautions?
Avoid excess dosage.
At What Temperature Should it be Stored?
Store it at room temperature.
Schedule : H Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
Glim C(Gliclazide) : Frequently Asked Questions
Q: What happens if Glim C is taken on an empty stomach?
A: Glim C should be taken 30 minutes before breakfast. Glim C promotes more appropriate insulin release and better glucose disposition when taken 30 minutes before breakfast than when taken with breakfast(1✔✔Trusted Source Influence of food intake on the absorption and effect of glipizide in diabetics and in healthy subjects
A: Sulfonylureas have been linked to an increased risk of drug-induced idiosyncratic liver disease. A diabetic patient developed acute icteric liver necro-inflammation after starting Glim C therapy(2✔✔Trusted Source Gliclazide-induced acute hepatitis
A: Glim C not only has a hypoglycemic action but also possesses antiplatelet activity by inhibiting platelet aggregation via the serotonin pathway(3✔✔Trusted Source Effects of gliclazide on platelet aggregation and the plasminogen activator inhibitor type 1 level in patients with type 2 diabetes mellitus
A: The use of oral diabetes medications during pregnancy is not advised due to known adverse effects on the fetus, such as congenital abnormalities, fetal hyperinsulinemia, and neonatal hypoglycemia(4✔✔Trusted Source Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy
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1. Influence of food intake on the absorption and effect of glipizide in diabetics and in healthy subjects - (https://pubmed.ncbi.nlm.nih.gov/7002565/)
3. Effects of gliclazide on platelet aggregation and the plasminogen activator inhibitor type 1 level in patients with type 2 diabetes mellitus - (https://pubmed.ncbi.nlm.nih.gov/20070990/#:)
4. Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy - (https://pubmed.ncbi.nlm.nih.gov/19109210/)
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