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Drug information on Zemi (320mg) (Gemifloxacin) from FDC Limited (Vista)

Zemi (320mg)

  Film coated tablet
FDC Limited (Vista)
Generic : Gemifloxacin
Pallavi Singh
Written & Compiled by Pharmacist Pallavi Singh, M. Pharmacy (Pharmacy Practice)
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Nov 23, 2017
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Medical Condition(s) for which Zemi (320mg) may be prescribed

Overview of Zemi (320mg)

• Gemifloxacin is a fluoroquinolone antibiotic; it is used for the treatment of bacterial infections.

Side effects of Zemi (320mg)

  Nervous system: Headache and dizziness

  Skin: Skin rash

  Digestive tract: Diarrhea, nausea, abdominal pain and vomiting

  Blood: Increase or decrease in white blood cells or platelets

  Liver: Increase in liver enzymes

  Heart: Prolonged QTc interval on ECG

  Others: Tendonitis, tendon rupture, peripheral neuritis, low blood glucose levels, allergic reactions, photosensitive reactions. Superinfection with Clostridium difficile can occur with prolonged use of the antibiotic

Dosage & When it is to be taken (Indications)

• The recommended adult dose of gemifloxacin is 320mg tablet taken orally once a day for five to seven days.

How to use Zemi (320mg)?

• Gemifloxacin should be taken with plenty of water.

When is Zemi (320mg) not to be taken? (Contraindications)

• Gemifloxacin is contraindicated in patients allergic to the drug or to other quinolones.

Warnings and Precautions for Zemi (320mg)

• The patient should consult the doctor in case of any pain and swelling or inflammation in joints.
• Caution should be taken while using it in elderly patients.

Other Precautions for Zemi (320mg)

• The medication should be avoided in pregnant women
• The dose should be reduced in patients with severe kidney disease
• Avoid in patients with myasthenia gravis due to possible exacerbation of muscle weakness
• Use with caution in patients with rheumatoid arthritis due to increased risk of tendon rupture

Drug Interactions of Zemi (320mg)

• Gemifloxacin may increase the chances of bleeding when given with warfarin.
Probenecid may increase the plasma concentration of gemifloxacin.
• The absorption of gemifloxacin is reduced when administered with supplements that contain iron, zinc or magnesium. These should be avoided 3 hours before and 2 hours after taking gemifloxacin.
• Gemifloxacin may increase the glucose-lowering effect of anti-diabetes drugs.
• The risk of tendonitis and tendon rupture may increase when administered with corticosteroids.
• The risk of heart rhythm abnormalities due to drugs that prolong QTc interval may increase with concomitant gemifloxacin.
• Gemifloxacin may reduce the serum concentration of the active metabolite of mycophenolate.
• Quinapril, sucralfate and sevelamer may reduce the concentration of gemifloxacin.

Storage Conditions for Zemi (320mg)

• Gemifloxacin should be stored at 15-30℃ temperature.

Disclaimer : Change in the rate of medication is possible and the rates shown maybe more or less than the rate displayed due to added GST and pricing changes made by the companies.
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