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Drug information on Zemi (320mg) (Gemifloxacin) from FDC Limited (Vista)

Zemi (320mg)

  Film coated tablet
FDC Limited (Vista)
Generic : Gemifloxacin
 65.00
320mg
5
Pallavi Singh
Written & Compiled by Pharmacist Pallavi Singh, M. Pharmacy (Pharmacy Practice)
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Nov 23, 2017
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Medical Condition(s) for which Zemi (320mg) may be prescribed


Overview of Zemi (320mg)

• Gemifloxacin is a fluoroquinolone antibiotic; it is used for the treatment of bacterial infections.

Side effects of Zemi (320mg)

  Nervous system: Headache and dizziness

  Skin: Skin rash

  Digestive tract: Diarrhea, nausea, abdominal pain and vomiting

  Blood: Increase or decrease in white blood cells or platelets

  Liver: Increase in liver enzymes

  Heart: Prolonged QTc interval on ECG

  Others: Tendonitis, tendon rupture, peripheral neuritis, low blood glucose levels, allergic reactions, photosensitive reactions. Superinfection with Clostridium difficile can occur with prolonged use of the antibiotic

Dosage & When it is to be taken (Indications)

• The recommended adult dose of gemifloxacin is 320mg tablet taken orally once a day for five to seven days.

How to use Zemi (320mg)?

• Gemifloxacin should be taken with plenty of water.

When is Zemi (320mg) not to be taken? (Contraindications)

• Gemifloxacin is contraindicated in patients allergic to the drug or to other quinolones.

Warnings and Precautions for Zemi (320mg)

• The patient should consult the doctor in case of any pain and swelling or inflammation in joints.
• Caution should be taken while using it in elderly patients.

Other Precautions for Zemi (320mg)

• The medication should be avoided in pregnant women
• The dose should be reduced in patients with severe kidney disease
• Avoid in patients with myasthenia gravis due to possible exacerbation of muscle weakness
• Use with caution in patients with rheumatoid arthritis due to increased risk of tendon rupture

Drug Interactions of Zemi (320mg)

• Gemifloxacin may increase the chances of bleeding when given with warfarin.
Probenecid may increase the plasma concentration of gemifloxacin.
• The absorption of gemifloxacin is reduced when administered with supplements that contain iron, zinc or magnesium. These should be avoided 3 hours before and 2 hours after taking gemifloxacin.
• Gemifloxacin may increase the glucose-lowering effect of anti-diabetes drugs.
• The risk of tendonitis and tendon rupture may increase when administered with corticosteroids.
• The risk of heart rhythm abnormalities due to drugs that prolong QTc interval may increase with concomitant gemifloxacin.
• Gemifloxacin may reduce the serum concentration of the active metabolite of mycophenolate.
• Quinapril, sucralfate and sevelamer may reduce the concentration of gemifloxacin.

Storage Conditions for Zemi (320mg)

• Gemifloxacin should be stored at 15-30℃ temperature.



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