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Drug information on Cymevene (500 mg) (Ganciclovir) from Roche Pharmaceuticals (RND Laboratories Pvt Ltd)

Cymevene (500 mg)   Injection Roche Pharmaceuticals (RND Laboratories Pvt Ltd) Generic : Ganciclovir	1,872.00 500mg/1vial 1Vial

Information Checked by Dhanalakshmi Chinnuswamy, Diploma in Pharmacy, MBA (Healthcare)

Further Checked by The Medindia Medical Review Team on Jan 03, 2011

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Bone Marrow Transplantation

Conjunctivitis

Corneal Ulcer

•  Body as a Whole: Fever, chills, infection, enlarged abdomen, weakness, chest pain, edema, headache, injection site inflammation, uneasiness and pain.

•  Gastrointestinal: Diarrhea, loss of appetite, vomiting, abnormal liver function test, mouth ulcer, constipation, indigestion and eructation.

•  Blood: Decrease in all types of blood cells.

•  Respiratory: Increased cough and difficulty in breathing.

•  Central Nervous System: Abnormal dreams, anxiety, confusion, depression, dizziness, dry mouth, sleeplessness, epilepsy, drowsiness, abnormal thinking and tremor.

•  Skin: Hair loss and dry skin.

•  Eye and ENT: Abnormal vision, taste perversion and ringing in the ear.

•  Metabolic: Changes in liver enzymes and weight loss.

•  Heart: High blood pressure, inflammation of vein and dilatation of blood vessels.

•  Genitourinary: Kidney failure, abnormal kidney function and urinary frequency.

•  Musculoskeletal: Joint/muscle pain, leg cramps and muscle weakness.

IV: The recommended initial dosage is 5 mg/kg (given intravenously at a constant rate over 1 hour) every 12 hours for 14 to 21 days. Maintenance: 5 mg/kg over 1 hour once daily, 7 days per week, or 6 mg/kg once daily, 5 days per week.

It comes as a solution for injection to be administered by a healthcare provider into the vein. It also comes as a capsule to take by mouth.

Hypersensitivity.

• Avoid rapid or bolus (large amount) administration.

• Caution should be exercised in patients with history of mental illness, epilepsy, kidney or liver disease, eye problems, decrease in blood counts, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness, drowsiness, or blurred vision, do not drive a car or operate machinery while taking this medication.

• Avoid any vaccination, alcohol consumption while taking this medication.

•

It may lead to poor blood clot, avoid injury or bruising.

Store it at controlled room temperature (25°C to 30°C) and in an airtight container. Keep away from children.