Drug information on Epraz-RD (Esomeprazole) from ASTRA IDL LTD

Medical Condition(s) for which Epraz-RD may be prescribed

---

•  Central Nervous System: Headache, dizziness, drowsiness, aggression, agitation, depression, hallucination.

•  Skin: Itching, hair loss, severe allergic reactions, photosensitivity, blistering.

•  Eye and ENT: Blurred vision.

•  Gastrointestinal: Flatulence, abdominal pain, stomach upset, nausea, diarrhea, dry mouth, constipation, GI fungal infection, inflammation of pancreas and intestine, mouth ulcer, taste disturbance.

•  Genitourinary: Breast enlargement in men, kidney disorder.

•  Liver: Occurrence of confusion, altered level of consciousness and coma as a result of liver failure(Hepatic encephalopathy) , liver failure, inflammation of liver with or without jaundice.

•  Blood: Decrease in white blood cells.

•  Local: Injection-site reactions including mild local redness and itching with IV administration.

•  Musculoskeletal: Muscular weakness, muscle pain.

•  Respiratory: Asthma, respiratory tract infection.

•  Miscellaneous: Severe allergic reaction/shock.

GERD: 20 or 40 mg is given once daily for 4-8 weeks. In children ages 1-11, the dose is 10 or 20 mg daily.
H. pylori: 40 mg is administered once daily in combination with amoxicillin and clarithromycin for 10 days.
NSAID-induced ulcers: 20 to 40 mg daily for 6 months.
Zollinger-Ellison syndrome is treated with 40 mg twice daily.

It comes as a tablet or capsule to take by mouth, once a day, one hour before meal.

Hypersensitivity.
♦ It should not be co-administered with Methotrexate, clopidogrel and atazanavir.

• Caution needed for children, pregnancy and breastfeeding women.

• It may cause malignancy and liver impairment.

• While taking this medication, there is an increased risk of developing certain infections such as community-acquired pneumonia.

Take properly as per your doctor's advice.

Injection: Powder for injection: Store at (20 - 25°C). Protect from light. Reconstituted solution for injection should be stored at room temperature up to 30°C and administered within 12 hr after preparation.

♦ Safety Labeling Changes Approved By FDA