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Doxapram is a respiratory stimulant, prescribed for airway obstruction and drug induced respiratory depression. It alters neurotransmitters in the brain that stimulate breathing center.

Drug information on Doxapram (Doxapram) from Khandelwal Laboratories Pvt. Ltd.


Khandelwal Laboratories Pvt. Ltd.
Generic : Doxapram
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Medical Condition(s) for which Doxapram may be prescribed

Side effects of Doxapram

  Central Nervous Systems: Fever, flushing, tingling, feeling warmth, burning or hot sensation, disorientation, hallucinations, headache, dizziness, hyperactivity, involuntary movements, increased deep tendon reflexes and convulsions.

  Respiratory: Difficulty in breathing, increased cough, fast breath and asthma.

  Heart: Inflammation of vein, irregular heart rate, chest pain, tightness in chest and high blood pressure.

  Gastrointestinal: Nausea, vomiting and diarrhea.

  Genitourinary: Uncontrolled urination, urinary retention and elevation of Blood Urea Nitrogen and albumin in urine.

  Blood: Breakdown of blood cells, anemia and decrease in white blood cells.

  Skin: Sweating and itching.

  Eye: Pupil dilation.

Dosage & When it is to be taken (Indications)

Adult: IV- Post-op resp depression- Initial: 0.5-1.5 mg/kg via injection. May repeat hourly if needed. Max total: 4 mg/kg.
Acute resp failure- 1.5-4 mg/min via infusion.

How to use Doxapram?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

When is Doxapram not to be taken? (Contraindications)

Contraindicated in patients with epilepsy, blood clot in lungs, stroke, heart failure, severe high blood pressure and hypersensitivity.

Warnings and Precautions for Doxapram

Monitor blood pressure, pulse rate, kidney and liver functions regularly while taking this medication.

• Avoid rapid administration; otherwise it will lead to breakdown of blood cells.

• Patient may develop with increased risk of low blood pressure or difficulty in breathing; if so consult with your doctor.

• Caution should be exercised in patients with history of heart, liver or kidney disease, during pregnancy and breastfeeding.

Other Precautions for Doxapram

Patient must be provided with adequate oxygen and ventilation.
Avoid excess/low dosage.

Storage Conditions for Doxapram

Store it at room temperature (20°-25°C) and in an airtight container.

Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Disclaimer : The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including GST. These are only approximate indicative prices of the drug.
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Substitutes for Doxapram

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