Donep (Donepezil) Drug Price and Information

Donepezil (Donep) is a cholinesterase inhibitor, prescribed for dementia of Alzheimer's disease.  It works by increasing the amount of acetylcholine in the brain, which helps in improving mental function.
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Donep - Alkem Laboratories Ltd. (Pentacare)

Donep  Tablet  

Generic : Donepezil
10 Tablets
Price Updated on August 8, 2019
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Drug information on Donep from Alkem Laboratories Ltd. (Pentacare)


When is Donep prescribed?

It is prescribed for -

What should be the dose and frequency?

Adult: PO- Initial: 5 mg/day in the evening, up to 10 mg/day after 4-6 week.

What are the common side effects of Donep

Most frequent : Nausea, diarrhea, vomiting, muscle cramps, fatigue and loss of appetite.

Body as a Whole : Headache, generalized pain and fatigue.

Heart : Fainting.

Blood : Bruising.

Metabolic : Decreased weight.

Musculoskeletal : Muscle cramps and joint inflammation.

Central Nervous System : Sleeplessness, dizziness, depression, abnormal dreams and drowsiness.

Genitourinary : Frequent urination.

How to use Donep?

It comes as a tablet to take by mouth, with or without food.


In which conditions should Donep be avoided?



What are the Precautions needed with Donep

Caution should be exercised in patients with history of heart disease, stomach problems, liver or kidney disease, breathing problems, urinary obstruction, brain tumor, head injury, seizures, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause drowsiness, dizziness, or fainting, do not drive a car or operate machinery while taking this medication.

It should not be used in children.

Are there any additional Precautions?

Avoid excess dosage.

At What Temperature Should it be Stored?

Store it at controlled room temperature (15° to 30°C), and in an airtight container.

Donep(Donepezil) : Frequently Asked Questions

Q: When is the best time to take Donep?

A: Donep is usually taken once daily, with or without food, in the evening before going to bed. Donep should be taken every day at the same time(1 Trusted Source

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Q: Does Donep cause weight loss?

A: The most common adverse effects of Donep are the gastrointestinal side effects that can cause loss of appetite and weight loss. It can cause weight loss in 5% of patients. The incidence rises with increasing doses(2 Trusted Source
Rivastigmine Improves Appetite by Increasing the Plasma Acyl/Des-Acyl Ghrelin Ratio and Cortisol in Alzheimer Disease

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Q: Does Donep cause gastric problems?

A: Donep may cause an increase in gastric acid secretion. Donep should be used with caution in patients at risk of developing ulcer disease, and GI bleeding symptoms must be monitored(3 Trusted Source

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Q: Who should not take Donep?

A: Patients with known hypersensitivity to Donep hydrochloride or piperidine derivatives should not take Donep(3 Trusted Source

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Q: What happens if Donep is taken more than the recommended dose?

A: Donep overdose can cause severe nausea, vomiting, sweating, and salivation. Bradycardia, hypotension, respiratory depression, collapse, muscle weakness, and seizures are all possible side effects(3 Trusted Source

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  • 1. Donepezil - (
  • 2. Rivastigmine Improves Appetite by Increasing the Plasma Acyl/Des-Acyl Ghrelin Ratio and Cortisol in Alzheimer Disease - ( )
  • 3. Donepezil - ( )
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