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Drug information on Docespera (Polysorbate) from Indoco Remedies Ltd.


Indoco Remedies Ltd.
Generic : Docetaxel
Combination of Generics : Docetaxel, Polysorbate
Dhanalakshmi Chinnuswamy
Further Checked by The Medindia Medical Review Team on February, 2, 2017
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Side effects of Docetaxel

  Heart: Low blood pressure, abnormal heart rhythm, blood clot in deep vein, ECG abnormalities, heart attack, blood clot in the lung, and fainting.

  Central Nervous System: Weakness, neurosensory and neuromotor symptoms, confusion, seizures, transient loss of consciousness.

  Skin: Hair loss, severe allergic reactions, nail color changes.

  Eye and ENT: Inflammation of conjunctiva, tears, transient visual disturbances including flashes, flashing lights, and blurred vision.

  Gastrointestinal: Mouth ulcer, severe diarrhea, nausea, vomiting, taste perversion, abdominal pain, loss of appetite, inflammation small intestine of colon, constipation, dehydration associated with GI reactions, duodenal ulcer, GI hemorrhage, GI perforation, ileus, intestinal obstruction.

  Genitourinary: Kidney failure.

  Blood: Decrease in white blood cells, platelets, anemia, bleeding episodes.

  Liver: Increased level of liver enzymes, hepatitis.

  Hypersensitivity: Severe hypersensitivity reactions.

  Local: Infusion-site reactions, inflammation of vein, redness or dryness of skin, and swelling of vein.

  Metabolic: Fluid retention.

  Musculoskeletal: Joint pain, muscle pain.

  Respiratory: Acute lung swelling, acute respiratory distress syndrome, difficulty in breathing, stiffening and scarring of lung tissue.

  Miscellaneous: Infection, fever in absence of infection, death due to infection, non septic death, chest pain, diffuse pain, radiation recall phenomenon.

When is Docetaxel not to be taken? (Contraindications)

Contraindicated in patients with previous severe hypersensitivity reaction to this drug, the solvent or polysorbate 80, severe decrease in white blood cells, pregnancy, severe liver impairment.

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