Colifate (Colistimethate Injection) Drug Price and Information

Colistimethate Injection (Colifate) is a polymyxin antibiotic, prescribed for infections caused by bacteria. The antibiotic fights against the bacteria in the body.  
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Colifate - Briskon Laboratories

Colifate  Suspension   

Generic : Colistimethate Injection
Price Updated on August 8, 2019
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Drug information on Colifate from Briskon Laboratories


When is Colifate prescribed?

It is prescribed for -

What should be the dose and frequency?

PO- GI infections; Bowel sterilization- 1.5-3 million units 3 times/day.
IV/IM- GI infections; Bowel sterilization as colistimethate Na: 6 million units/day in 3 divided doses. Max: 6-million units/24 hour.
Inhalation- Adjunct to antimicrobial therapy in respiratory infections as colistimethate Na: 1-2 million units twice daily. Max: 2 million units 3 times/day for up to 3 month in frequent recurrent infections.

What are the common side effects of Colifate

Gastrointestinal: Gastrointestinal upset.

Central Nervous System: Tingling of extremities and tongue, slurred speech, dizziness and fainting.

Skin : Generalized itching, hives and rash.

Body as a Whole : Fever.

Respiratory : Respiratory disorder and shortness of breath.

Genitourinary : Kidney damage and decreased urine output.

How to use Colifate?

It comes as a syrup to take by mouth.


In which conditions should Colifate be avoided?



What are the Precautions needed with Colifate

Caution should be exercised in patients with history of preexisting kidney impairment, disorders of neuromuscular transmission, during pregnancy and lactation.

Monitor liver enzyme level and Blood Urea Nitrogen level regularly while on treatment.

Are there any additional Precautions?

Avoid excess dosage and alcohol consumption.

At What Temperature Should it be Stored?

Store reconstituted solution in refrigerator at 2°-8°C (36°-46°F) or between 20°-25°C

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