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Duplat (50 mg) is a platinum-based chemotherapy agent, prescribed for ovarian cancer, bladder cancer and metastatic testicular tumors either alone or with other medications.  It stops cancer cell growth.

Drug information on Duplat (50 mg) (Cisplatin) from Samarth Pharma Pvt. Ltd.

Duplat (50 mg)

Samarth Pharma Pvt. Ltd.
Generic : Cisplatin
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Medical Condition(s) for which Duplat (50 mg) may be prescribed

Side effects of Duplat (50 mg)

   Toxic effects : Nephrotoxicity (kidney damage) and ototoxicity (ear damage).

   Severe effects : Stroke, heart attack, electrolyte disturbances and allergic reactions.

   Gastrointestinal : Loss of appetite, nausea and vomiting.

   ENT : Ringing in the ear, loss of hearing and deafness.

Dosage & When it is to be taken (Indications)

Adult: IV- Metastatic ovarian cancer As monotherapy: 100 mg/m2 per cycle, given as a single dose once every 4 week.
For combination therapy with cyclophosphamide: 75-100 mg/m2 on day 1 of every 4-week cycle. Metastatic testicular tumors 20 mg/m2/day for 5 days per cycle. Advanced bladder cancer 50-70 mg/m2 per cycle once every 3-4 week.

How to use Duplat (50 mg)?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

When is Duplat (50 mg) not to be taken? (Contraindications)

Contraindicated in patients with hearing impairment, kidney impairment and hypersensitivity.

Warnings and Precautions for Duplat (50 mg)

Caution should be exercised in patients with history of bone marrow suppression, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast-feeding.

• Monitor complete blood counts, ear and neurological functions regularly while taking this medication.

• Patients may develop with increased risk of nephrotoxicity (kidney damage with irritation), drink adequate fluids to prevent damage.

• Avoid vaccination while taking this medication.

• It may develop new type of cancer; if you have any doubt consult with your doctor regarding this.

Other Precautions for Duplat (50 mg)

Avoid excess dosage.

Storage Conditions for Duplat (50 mg)

This drug is used only under the supervision of physician.

Schedule : G  Drugs that are to be used only under medical supervision.

Disclaimer : The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including GST. These are only approximate indicative prices of the drug.
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Substitutes for Duplat (50 mg)

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