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Drug information on Trycef 1 gm Inj. (Ceftriaxone) from Sandhya Healthcare Remedies Impel Pvt. Ltd.

Trycef 1 gm Inj.   Injection Sandhya Healthcare Remedies Impel Pvt. Ltd. Generic : Ceftriaxone	58.00 1gm Vial

Information Checked by Dhanalakshmi Chinnuswamy, Diploma in Pharmacy, MBA (Healthcare)

Further Checked by The Medindia Medical Review Team on February, 2, 2017

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Infective Endocarditis

Lyme Disease

Meningitis

Otitis Media

Pneumonia

Shigellosis

Syphilis

Typhoid and Paratyphoid Enteric Fevers

•  Central Nervous System: Dizziness, Headache.

•  Gastrointestinal: Diarrhea, nausea and vomiting.

•  Blood: High concentration of eosinophils, platelet counts in the blood, decrease in white blood cells, low prothrombin levels, bleeding.

•  Lab tests: Increase in liver enzyme, elevated BUN (Blood urea, nitrogen).

•  Local: Indurations/tightness/warmth.

•  Genitourinary: Vaginal inflammation.

•  Miscellaneous: Fatal ceftriaxone-calcium precipitates in lung and kidneys of neonates.

Middle ear infection: Children - IM A single dose of 50 mg/kg (max, 1 gram) is recommended.
Meningitis in children: Children - IV: Recommended initial dose is 100 mg/kg (max, 4 gram), followed by 100 mg/kg/day (max, 4 gram/day) for 7 to 14 days.
Skin or Skin Structure Infections: Children - IV/IM: Recommended daily dosage is 50 to 75 mg/kg once a day or in equally divided doses twice daily (max, 2 gram/day).
Surgical Prophylaxis: Adults - IV: 1 gram as a single dose 30 min to 2 hours before surgery.
Uncomplicated Gonococcal Infections: Adults - IM: 250 mg as single dose.
Miscellaneous Infections: Adults - IV: Usual adult daily dosage is 1 to 2 g once a day or in equally divided doses twice daily, depending on the type and severity of infection (max, 4 gram/day).
Children- IV: Recommended daily dose is 50 to 75 mg/kg IV once a day or in divided doses every 12 h (max, 2 gram/day). IV/IM: Recommended daily dose is 50 to 75 mg/kg IV/IM in divided doses every 12 h (max, 2 gram/day).
Acute Bacterial Otitis Media Persistent/Treatment Failure: Children - IM/IV 50 mg/kg/ IM or IV (not to exceed 1 gram) daily for 3 days.
Pelvic Inflammatory Disease (mild to moderate): Adults - IM 250 mg given IM as a single dose with doxycycline 100 mg orally twice daily for 14 days, with or without metronidazole 500 mg orally twice daily for 14 days.
Uncomplicated Gonococcal Infections: Adults - IM 125 mg given IM as a single dose.
Typhoid:Adult- IV: 4gm/day for 2 days, followed by 2g/day. Child- 75mg/day for 2 days.

It comes as a solution for injected to be administered intravenously (into a vein) or intramuscularly (into a muscle), by a healthcare provider.

Hypersensitivity to cephalosporins; neonates. Do not use calcium or calcium-containing solutions or products with or within 48 hours of ceftriaxone administration due to risk of calcium-ceftriaxone precipitate formation in neonates.

• Caution should be exercised in patients with history of penicillin allergy; severe renal impairment; pregnancy and lactation; problem with digestive system, especially colitis (inflammation of the large intestine), malnutrition (you do not eat or cannot digest the nutrients needed for good health), super infection.

• Be sure for the full course of treatment. If you do not, the medicine may not clear up your infection completely.

Avoid long-term or repeated use, otherwise it will secondary infection.

Injection: Store below 25°C. Store it at room temperature and keep away from children.