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Drug information on Reflin (1g) (Cefazolin) from Ranbaxy Laboratories Ltd. (Pharma)

Reflin (1g)

Ranbaxy Laboratories Ltd. (Pharma)
Generic : Cefazolin
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Medical Condition(s) for which Reflin (1g) may be prescribed

Side effects of Reflin (1g)

  Central Nervous System: Hyperactivity.

  Gastrointestinal: Abdominal pain, anal itching, loss of appetite, inflammation of colon, diarrhea, nausea, fungal infection of mouth, stomach cramps, vomiting.

  Genitourinary: Genital itching (including genital fungal infection, vaginal inflammation, vulvar itching).

  Liver: Liver inflammation.

  Blood: Anemia, bleeding, decrease in white blood cells, platelets.

  Lab tests: Increased level of liver enzymes, prolonged blood clotting time.

  Local: Pain, inflammation of veins.

  Musculoskeletal: Tightness of muscle.

  Genitourinary: Increased BUN (Blood, urea, Nitrogen) and creatinine, kidney function impairment, toxic nephropathy.

  Miscellaneous: Allergy (including anaphylaxis, drug fever, eosinophilia, severe allergic reactions, toxic hives), super infection.

Dosage & When it is to be taken (Indications)

IV/IM- Susceptible infections 0.5-1 g 6-12 hourly. Max: 6 g/day, up to 12 g/day in severe infections.
Surgical prophylaxis- 1 g 30-60 minutes pre-op, followed by 0.5-1 g during surgery for lengthy procedures. Continue with 0.5-1 g 6-8 hourly post-op for 24 hour.

How to use Reflin (1g)?

It comes as a solution for injection, to be administered by a healthcare provider. It is usually administrated by either intramuscular injection (injection into a large muscle) or intravenous infusion (injection into a vein).

When is Reflin (1g) not to be taken? (Contraindications)


Warnings and Precautions for Reflin (1g)

Caution should be exercised in patients with history of liver, kidney, and gastrointestinal diseases.

• It may harmful to kidney function, pregnancy and breast feeding.

• Consider possibility of pseudo membranous colitis in patients who present with diarrhoea after antimicrobial usage.

• Risk of seizures in patients on high doses, especially in kidney failed patients.

• It may decrease prothrombin activity; monitor prothrombin time in patients at risk e.g. those on anticoagulant treatment, prolonged antimicrobial treatment or those with kidney or liver impairment.

Other Precautions for Reflin (1g)

Avoid long-term use, otherwise it will cause secondary infection.

Storage Conditions for Reflin (1g)

Injection: Store at 25°C.Store in refrigerator. Do not freeze the medication.

Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Disclaimer : Change in the rate of medication is possible and the rates shown maybe more or less than the rate displayed due to added GST and pricing changes made by the companies.
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